Pediatrics Archives | 第 3 页，共 7 页 | Certara

Novartis

Case Study

Simcyp 年龄定义功能助力优化新生儿 Everolimus 给药方案

Everolimus (Afinitor®) was recently approved as adjunctive therapy for tuberous sclerosis complex (TSC)-associated partial seizures…

Certara2021 年 8 月 26 日

PTC Therapeutics

Case Study

Using PBPK for Label Recommendations in Rare Disease: Deflazacort for Duchenne Muscular Dystrophy

Certara2021 年 8 月 20 日

Vertex

Case Study

Determining Exposures when Transitioning Between Combination Treatments in Cystic Fibrosis: Trikafta

Many cystic fibrosis (CF) patients take several medications at one time to manage symptoms and…

Certara2021 年 7 月 14 日

GBT

Case Study

治疗镰状细胞病的 Voxelotor：无需任何临床研究，利用剂量预测模型进行 DDI 预测

In November 2019, the US FDA granted accelerated approval for Oxbryta™ (voxelotor) tablets for the…

Certara2021 年 7 月 14 日

On-Demand Webinar

将 PBPK 模型应用于儿科药物开发的最佳实践框架

Pediatric PBPK models have broad application in the drug development process and are being used…

Certara2021 年 4 月 20 日

White Paper

利用 Simcyp® PBPK 推进儿科药物研发

Certara2021 年 3 月 4 日

Case Study

Galderma AKLIEF®（曲法罗汀）获得了 FDA 批准

In October 2019, Galderma announced that the U.S. FDA approved AKLIEF® (trifarotene) Cream, 0.005% for the…

Certara2020 年 11 月 9 日

Blog

The research to accelerate cures and equity (RACE) for children act: Changing the landscape of pediatric cancer drug development

3 key tips to set your pediatric program up for success with the RACE for…

Certara2020 年 7 月 14 日

Publication

Use of Modeling and Simulations to Determine Raltegravir Dosing in Neonates: A Model for Safely and Efficiently Determining Appropriate Neonatal Dosing Regimens: IMPAACT P1110

Certara2020 年 1 月 17 日

Publication

Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

Maternal-Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

Certara2020 年 1 月 17 日

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