在机制建模和模拟领域打下坚实的基础
美国食品及药物管理局（FDA）和其他监管机构已将基于模型的定量药物开发方法确定为提高效率的宝贵工具。
我们的研习班重点关注如何优化使用化合物特异性体外和体内数据以及系统特异性信息，以模拟和了解药物在各种目标人群中的行为。这种综合方法为有关新药研究（IND）和新药申请（NDA）的决策提供信息，并协助临床研究的最佳设计和实施。最终目的是提高提交监管审批的质量。
这些研习班为以模型为基础的方法提供了坚实的基础，并不仅仅针对有实践经验的个人。这些内容适用于在药物代谢、ADME、临床药理学、药代动力学、PBPK 和 PK/PD 领域工作的工业界、学术界和研究机构的高级管理人员和科学家。
如需了解更多信息，请查看 Simcyp 研习班常见问题解答。
浏览即将举办的 Simcyp 研习班Hear from Our Participants:
Comprehensive Knowledge: “The workshop provided comprehensive knowledge of physiological PBPK modeling using the Simcyp Simulator. The exercises that were beneficial to gain hands on experience.” Konstantina Koliopoulou
Ease of Material: “The material was easier to go through compared to concentrated workshops.” Aurelija Radzeviciene
Real-World Application: “Participating in this workshop focused on PBPK modeling with Simcyp offered a multitude of positive aspects that could greatly benefit my research project. The hands-on experience was invaluable as it allowed me to apply theoretical knowledge to real-world scenarios, enhancing my proficiency and confidence in using PBPK models.” Laura Olivo
线下教学
Simcyp 线下教学计划可在您的现场提供定制培训课程。该计划既能满足科学家的小规模培训要求，也能满足他们的大规模研习班式培训要求。我们可以整合：
- 入门或进阶 Simulator 培训
- 涵盖关键主题和基于模型的药物开发当前趋势的重点研习班
- 通过实际应用 Simulator 的实践练习提供专业指导
- 为 Simcyp 内部工作组提供面对面支持
视频教程、演示和技巧
我们有 Simcyp 科学各方面的视频教程，并提供使用 Simcyp Simulator 的演示和实用技巧。本资料既可作为老用户的复习资料，也可作为新用户的入门资料。
该资源可通过 Simcyp 会员专区获取，其中还包括近期网络研讨会的录像和 Simcyp 免费 ADME 工具。E-learning 计划仅限于 Simcyp Simulator 用户和 Simcyp Consortium 成员公司。
Bastek 主导 Simcyp 皮肤模型和心脏安全建模与模拟系统 - 心脏安全模拟器的开发。他还是波兰克拉科夫 Jagiellonian 大学药学院生物制药学终身教授。
Dr. Sibylle Neuhoff is a Senior Scientific Advisor and Deputy Head of the Translational Science Group at Certara Predictive Technologies, where she leads the Transporter Group within Simcyp. With over 25 years of experience in the fields of transport, transporters, and their mechanisms, Dr. Neuhoff is a recognized expert in PBPK/PD modeling, oral drug absorption, transport, metabolism, and toxicity. Her extensive research is documented in numerous peer-reviewed journal articles (Sibylle Neuhoff (0000-0001-8809-1960) – ORCID).
Dr. Neuhoff holds a degree in Chemistry from the Goethe University in Frankfurt am Main, Germany, and earned her PhD from the Department of Pharmacy at Uppsala University, Sweden, in 2006. Her current research focuses on the pharmacogenomics of drug-metabolizing enzymes and transporters, drug disposition and pharmacodynamics, ligand interactions with human metabolizing enzymes and transporters, endogenous biomarkers, and innovative approaches to simulate and predict metabolic clearance, drug-drug interactions, and transporter-related interactions in both healthy subjects and patient populations.
Dr. Neuhoff has taught over 50 PBPK workshops on the Simcyp™ PBPK Simulator, Simcyp Animal, and the Simcyp In Vitro Data Analysis (SIVA) toolkit, covering topics such as MIDD, Transporter, FIH, DDI, and Best Practices. She is regularly invited as speaker to present at national and international conferences and meetings.
Additionally, Sibylle is an active member of The International Transporter Consortium.
Iain 领导的科学团队负责进一步开发基于群体生理的 PK/PD 模拟器，以满足 Simcyp 联盟成员的需求。在加入 Certara 之前，他在辉瑞全球研发部的药物动力学、动力学和代谢部门工作了 12年。
Bastek 主导 Simcyp 皮肤模型和心脏安全建模与模拟系统 - 心脏安全模拟器的开发。他还是波兰克拉科夫 Jagiellonian 大学药学院生物制药学终身教授。
Dr. Sibylle Neuhoff is a Senior Scientific Advisor and Deputy Head of the Translational Science Group at Certara Predictive Technologies, where she leads the Transporter Group within Simcyp. With over 25 years of experience in the fields of transport, transporters, and their mechanisms, Dr. Neuhoff is a recognized expert in PBPK/PD modeling, oral drug absorption, transport, metabolism, and toxicity. Her extensive research is documented in numerous peer-reviewed journal articles (Sibylle Neuhoff (0000-0001-8809-1960) – ORCID).
Dr. Neuhoff holds a degree in Chemistry from the Goethe University in Frankfurt am Main, Germany, and earned her PhD from the Department of Pharmacy at Uppsala University, Sweden, in 2006. Her current research focuses on the pharmacogenomics of drug-metabolizing enzymes and transporters, drug disposition and pharmacodynamics, ligand interactions with human metabolizing enzymes and transporters, endogenous biomarkers, and innovative approaches to simulate and predict metabolic clearance, drug-drug interactions, and transporter-related interactions in both healthy subjects and patient populations.
Dr. Neuhoff has taught over 50 PBPK workshops on the Simcyp™ PBPK Simulator, Simcyp Animal, and the Simcyp In Vitro Data Analysis (SIVA) toolkit, covering topics such as MIDD, Transporter, FIH, DDI, and Best Practices. She is regularly invited as speaker to present at national and international conferences and meetings.
Additionally, Sibylle is an active member of The International Transporter Consortium.
Iain 领导的科学团队负责进一步开发基于群体生理的 PK/PD 模拟器，以满足 Simcyp 联盟成员的需求。在加入 Certara 之前，他在辉瑞全球研发部的药物动力学、动力学和代谢部门工作了 12年。
