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What is Pharmacodynamics?

Starting with definitions is always helpful… so after defining pharmacokinetics, a definition for pharmacodynamics is in order. The definition of pharmacodynamics (PD) is much less controversial than the definition for pharmacokinetics. The word pharmacodynamics is from two Greek words (see wikipedia for more): pharmakon: Drug dynamikós : force or power Thus, pharmacodynamics is the study … Continued

什么是药代动力学?

你可能会认为这是个简单的问题,尤其是对药代动力学专家来说。这个问题充满争议,每个科学家都有自己的观点。我认为这是因为药代动力学的定义很简单,而药代动力学科学的范围却很广。The word pharmacokinetics is from two greek words (see … Continued

Why Have a Blog About PK and PD?

Many blogs you will find on the internet are related to personal ventures, technology, or hobbies … all topics that are suited to the light-hearted fare that is common in the blogosphere. I believe that blogs can communicate knowledge in unique ways to a broad audience. Instead of developing a blog about my personal life, … Continued

Population Pharmacokinetic/Pharmacodynamic Model for a C.E.R.A. in Both ESA-naive and ESA-treated Chronic Kidney Disease Patients with Renal Anemia

This study aimed to develop a population pharmacokinetic/pharmacodynamic (PK/PD) model for C.E.R.A., a continuous erythropoietin receptor activator. C.E.R.A. is administered via intravenous (IV) and subcutaneous (SC) routes once every 2 weeks (Q2W) or once every 4 weeks (Q4W), respectively, to correct or maintain hemoglobin levels in chronic kidney disease (CKD) patients.

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