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Forging the next frontier with QSP

The Certara Quantitative Systems Pharmacology (QSP) group is a global organization focused on the impactful application of QSP and mechanistic PKPD modeling and simulation in drug discovery and development.

We are leading several first-of-its-kind QSP Consortia with more than 10 global pharmaceutical companies and have a rapidly expanding consultancy portfolio. Our QSP scientists work in close collaboration with other Certara staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D.

We are seeking highly motivated and talented QSP modelling experts at all levels, who share our passion for using quantitative approaches to understand and impact complex drug discovery and development questions. Positions are available at various levels of experience across our global locations and for flexible, home-based roles.

QSP Research Associate

Our QSP scientists work in close collaboration with other staff and clients to generate and use state-of-the-art mechanistic models for decision making in pharmaceutical R&D. The models are designed in close dialogue with clients and developed with a view to creating user-friendly tools that will inform drug development programs from discovery to regulatory filing. For this role, you should have postdoctoral experience in systems modelling for drug discovery/ development teams and PhD (or equivalent) in life sciences, engineering, computer sciences, mathematics, physics or equivalent. It is also essential that you have solid understanding of PKPD, pharmacology and biology and its application in drug discovery and development.

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QSP Research Associate
Quantitative Systems Pharmacology Positions (All Levels)

Quantitative Systems Pharmacology Positions (All Levels)

We are seeking highly motivated and talented QSP modelling experts at all levels, who share our passion for using quantitative approaches to understand and impact complex drug discovery and development questions. Besides our well-established leadership in applied QSP approaches in Immunology and Immuno-Oncology, we are now also the leading provider of QSP approaches in neuro-degenerative diseases through Certara’s recent acquisition of the In Silico Biosciences modelling platform.

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Piet vanderGraaf
Piet van der Graaf, PharmD, PhD 高级副总裁兼定量系统药理学负责人

Piet van der Graaf 现任 Certara 高级副总裁兼 QSP 负责人,同时也是莱顿大学系统药理学教授。Piet 是 2013 - 2016 年莱顿药物研究学术中心的研究主任。1999 - 2013 年,Piet 在辉瑞公司的研发生物学、药代动力学和药物代谢、以及临床药理学等部门担任过多种领导职务。Piet 于2012 - 2018 年担任 CPT: Pharmacometrics & Systems Pharmacology 的创始主编,随后成为 Clinical Pharmacology & Therapeutics 的主编。Piet 曾在伦敦国王学院师从诺贝尔奖获得者 Sir James Black,接受了临床医学的博士培训。他曾获得 2024 年美国临床药理学与治疗学会(ASCPT)颁发的 Gary Neil 药物开发创新奖,同时也是国际定量药理学会(ISoP)2021 年领袖奖的获得者。Piet 是英国药理学会的当选委员,在定量药理学和药物开发领域发表了超过 200 篇同行评议的论文。

AndrzejKierzek
Andrzej Kierzek,博士 系统建模主管

Andrzej 在计算生物学领域拥有 25 年经验,发表了用于分子网络动力学分析和基因组规模代谢网络约束建模的模型和软件。目前,他的科研工作集中于免疫肿瘤学和免疫原性。他是萨里大学系统生物学的客座教授。

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