Month: November 2016
Incorporation of an Electrochemical Driving Force for the Renal Transport of Metformin by OCT in a Physiologically-based Pharmacokinetic Model of the Interaction between Metformin and Cimetidine
Mechanistic Model-based Analysis of Biopharmaceutics Experiments—Application of In Vitro-In Vivo Extrapolation (IVIVE) Techniques within a PBPK Modeling Framework
In vitro dissolution testing is a critical component of drug product development and is often used as a surrogate for in vivo performance. While the range of (USP) standard methods have been developed and tested for many years, no single dissolution test or apparatus comprehensively maps the in vivo behaviour of the range of compound … Continued
US Environmental Protection Agency Uses Certara’s Simcyp Simulator to Support Toxicological Triage
PRINCETON, NJ – Nov. 10, 2016 – Certara today announced that the U.S. Environmental Protection Agency (EPA) is using its Simcyp Population-based Simulator to support the Agency’s high-throughput toxicity testing program.
Extension of Simcyp Brain Model for Proteins to Investigate Transferrin Receptor Transport
Certara Thought Leaders to Chair Strategic Pharmacology Discussions at AAPS Annual Meeting
PRINCETON, NJ – Nov. 9, 2016 – Certara announced that it will be chairing three sessions and participating in six more at the 2016 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting & Exposition.
IVIVC Software – Achieving Regulatory, Formulation and Manufacturing Success
In vitro-in vivo correlation (IVIVC) is an important, predictive mathematical tool in drug development, used to enhance product and process understanding with the ultimate goal of ensuring consistent performance throughout the product’s life cycle.
Phoenix WinNonlin 验证套件
The Phoenix WinNonlin Validation Suite is a desktop application that provides objective evidence of Phoenix WinNonlin functionality and streamlines the validation process through the use of automated tests accessed through a graphical user interface and validation document templates.
