Born from a collaboration between Professors Geoff Tucker and Amin Rostami-Hodjegan at the University of Sheffield, Simcyp has redefined PBPK modeling since 2001. Our Simcyp PBPK Simulator stands as the global gold standard for population-based simulation, guiding over 120 novel drug applications to market and delivering proven results.
Simcyp™ Consortium
25+ years of advancing PBPK through industry-leading scientific development and collaboration
Learn more about the Simcyp Consortium
Simcyp Consortium: Revolutionizing drug development
World-renowned technology
Informing over 120 novel drug applications, the Simcyp Simulator is a trusted platform used worldwide.
Enhanced drug labeling
Critical dosing recommendations for diverse patient groups including pediatric, pregnant subjects and those with organ impairment.
监管成功案例
With more than 375 label claims achieved virtually in lieu of clinical studies, Simcyp has pioneered the use of PBPK in regulatory filings.
Streamlined R&D
Fueling smarter decision-making, our technology reduces development time, saves critical R&D investments, and eliminates the guesswork from complex drug interactions.
Empowering the global scientific community
Simcyp believes in progress through education and collaboration. We award numerous grants and Simcyp Simulator licenses to hundreds of academic institutions and provide extensive training to scientists across industry, academia, and regulatory sectors.
The Simcyp Consortium – a meeting of minds
Innovation thrives through collaboration, and the Simcyp Consortium is proof of that. Representing 35+ leading biopharmaceutical companies worldwide, the Consortium actively shapes the scientific direction of the Simcyp PBPK Simulator, ensuring it evolves to meet industry needs. Every year, our members—pioneers in pharmaceuticals and biotechnology—come together to share insights, advance modeling techniques, and shape the future of PBPK science.

Simcyp 协会成员























Simcyp Workshops: Hands-on education
Education fuels innovation. That’s why we’ve hosted over 232 immersive PBPK workshops globally, certifying more than 8,500 scientists with cutting-edge modeling and simulation expertise.
Whether you’re a seasoned professional or new to PBPK, our workshops are designed to expand your knowledge and inspire new scientific possibilities.
Select from in-person, virtual, or tailored sessions to suit your goals. Your future in PBPK starts here.
"The workshop provided comprehensive knowledge of physiological PBPK modeling using the Simcyp Simulator. The exercises that were beneficial to gain hands on experience.”
Konstantina Koliopoulou

Simcyp Student Chapter: Inspiring the next generation
Innovation doesn’t stop with us—it extends to the next wave of pharmaceutical scientists. The Simcyp Student Chapter is a quarterly meeting designed that allows students with research licenses to collaborate, gain feedback, and refine their work in a supportive, community-driven environment.
If you’re interested in learning more about the Simcyp Student Chapter, please email {1}.
Simcyp’s commitment to scientific excellence and global education
The Simcyp team is globally recognized for its innovative research and development, consistently showcased at premier industry conferences and featured in esteemed scientific journals. Through meaningful collaborations, Simcyp advances academic teaching and research by providing sponsored licenses to over 110 universities and research institutions worldwide.
To celebrate research excellence and foster scientific advancement, the Simcyp Consortium presents two prestigious annual awards. These awards honor the ‘Most Informative Scientific Report’ and the ‘Most Effective Teaching Application’ utilizing the Simcyp Simulator. Winners receive financial support from Simcyp, empowering them to further their contributions to science and education.
Become a part of the legacy
Want to explore how Simcyp can elevate your drug development strategy? Engage with our workshops, join the Simcyp Consortium, or leverage our consultancy services to push the boundaries of possibility.
Together, we’ll rewrite what’s possible in patient care and drug development.
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