Pharmacokinetics and Safety of Oseltamivir in Patients with End-stage Renal Disease Treated with Automated Peritoneal Dialysis Publication Pharmacokinetics and Safety of Oseltamivir in Patients with End-stage Renal Disease Treated with Automated Peritoneal Dialysis Danielle Pillsbury2015 年 3 月 25 日
Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison Between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys Publication Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison Between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on…Danielle Pillsbury2015 年 2 月 15 日
Calculating the Elimination Rate Constant BlogKnowledge Base Calculating the Elimination Rate Constant The elimination rate constant is the rate at which drug is cleared from the body…Certara2015 年 2 月 2 日
Population Pharmacokinetics of Ceftolozane/Tazobactam in Healthy Volunteers, Subjects with Varying Degrees of Renal Function and Patients with Bacterial Infections Publication Population Pharmacokinetics of Ceftolozane/Tazobactam in Healthy Volunteers, Subjects with Varying Degrees of Renal Function and Patients with Bacterial Infections Ceftolozane/tazobactam is a novel antipseudomonal cephalosporin and a β-lactamase inhibitor in clinical development for treatment…Danielle Pillsbury2015 年 2 月 1 日
Common Misconceptions About Computer System Validation Blog 关于计算机系统验证的常见误解 Drug development professionals frequently use computer systems to help them understand the pharmacokinetics (PK) and…Certara2015 年 1 月 28 日
Using Modeling and Simulation to Quantify the PK of an Anti-HIV Drug for Babies Blog Using Modeling and Simulation to Quantify the PK of an Anti-HIV Drug for Babies As a scientist at Certara and proud Dad to my three kids, pediatric drug development…Certara2015 年 1 月 15 日
The Effect of Plasmapheresis on Blood Pressure in Voluntary Plasma Donors Publication The Effect of Plasmapheresis on Blood Pressure in Voluntary Plasma Donors Donor plasmapheresis involves the removal of a weight-adjusted volume of plasma and the return of…Danielle Pillsbury2015 年 1 月 1 日
Population Dose-response Analysis of Daily Seizure Count Following Vigabatrin Therapy in Adult and Pediatric Patients with Refractory Complex Partial Seizures Publication Population Dose-response Analysis of Daily Seizure Count Following Vigabatrin Therapy in Adult and Pediatric Patients with Refractory Complex Partial Seizures Vigabatrin is an irreversible inhibitor of γ-aminobutyric acid transaminase (GABA-T) and is used as an…Danielle Pillsbury2015 年 1 月 1 日
Pharmacokinetics of Injectable, Long-acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants Publication Pharmacokinetics of Injectable, Long-acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants Mother-to-child transmission (MTCT) of HIV-1 remains a global health problem. The World Health Organization (WHO…Danielle Pillsbury2015 年 1 月 1 日
Onartuzumab with or without Bevacizumab in Combination with Weekly Paclitaxel Does Not Prolong QTc or Adversely Affect Other ECG Parameters in Patients with Locally Recurrent or Metastatic Triple-negative Breast Cancer Publication Onartuzumab with or without Bevacizumab in Combination with Weekly Paclitaxel Does Not Prolong QTc or Adversely Affect Other ECG Parameters in Patients with Locally Recurrent or Metastatic Triple-negative Breast Cancer The purpose of this study was to examine the potential effect of onartuzumab, when administered…Danielle Pillsbury2014 年 12 月 17 日