Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects Publication Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects Explore how single‑tablet regimen matches exposure of separate tablets with comparable safety, analysed using Phoenix…Certara2023 年 7 月 20 日
Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome Publication Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome Madin–Darby canine kidney (MDCK) cells are widely used to study epithelial cell functionality. Their low…Certara2023 年 6 月 28 日
Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers Publication Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers Discover how no demographic covariates significantly affect granisetron patch PK; no dose adjustment needed, modelled…Certara2023 年 6 月 26 日
Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers Publication Safety and pharmacokinetic comparison between fenofibric acid 135 mg capsule and 110 mg enteric-coated tablet in healthy volunteers See how enteric‑coated tablet shows higher bioavailability and delayed peak vs capsule, analysed using Phoenix…Certara2023 年 6 月 16 日
Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples Publication Liquid Chromatography-Tandem Mass Spectrometry Method for Detection and Quantification of Meloxicam and 5′-Carboxymeloxicam in Oral Fluid Samples Learn how oral‑fluid LC‑MS/MS enables minimally invasive meloxicam PK/PD assessment, analysed using Phoenix WinNonlin.Certara2023 年 6 月 15 日
Leveraging Pharmacokinetic Modeling & Scientific Communications Expertise Advances Sarcoidosis Drug Program Case Study 利用药代动力学建模和科学传播专长推进肉样瘤病药物项目 Certara's support, from dose optimization to medical writing, helps pharmaceutical companies advance their research, make…Certara2023 年 6 月 1 日
Population pharmacokinetic model of ivermectin in mass drug administration against lymphatic filariasis Publication Population pharmacokinetic model of ivermectin in mass drug administration against lymphatic filariasis Find out how sex affects ivermectin peripheral distribution; infection status does not, modelled using Phoenix…Certara2023 年 6 月 1 日
American College of Toxicology 2026 Annual Meeting Conference American College of Toxicology 2026 Annual Meeting – – BoothKevin Snyder, PhD2023 年 5 月 24 日
Effects of plateau hypoxia on population pharmacokinetics and pharmacodynamics of metformin in patients with Type 2 diabetes Publication Effects of plateau hypoxia on population pharmacokinetics and pharmacodynamics of metformin in patients with Type 2 diabetes Explore how high‑altitude hypoxia increases metformin AUC and half‑life; PK‑PD modelling supports extended dosing intervals.Certara2023 年 4 月 28 日