Publication

Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms

Find out how CYP2C19 polymorphisms significantly affect esomeprazole exposure and half‑life, analysed using Phoenix WinNonlin.

Certara2023 年 9 月 29 日

Conference

KIC Korea 2026

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Certara2023 年 9 月 22 日

Publication

Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia

Explore how age increases dasatinib exposure; PopPK modelling supports lower dosing in elderly Chinese CML…

Certara2023 年 9 月 19 日

Publication

Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation

Discover how hemoglobin and eGFR drive imatinib PK variability; PopPK modelling supports caution in renal…

Certara2023 年 8 月 25 日

Publication

Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study

See how active uptake occurs at both BBB and BCSFB with no sex differences, analysed…

Certara2023 年 8 月 23 日

Publication

An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance

Learn how ARC patients show lower sulbactam exposure and higher clearance, supporting dose increases, analysed…

Certara2023 年 8 月 1 日

Publication

Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients

Find out how renal function and hypoalbuminemia alter ceftriaxone PK; current dosing remains appropriate, analysed…

Certara2023 年 7 月 24 日

Publication

Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects

Explore how single‑tablet regimen matches exposure of separate tablets with comparable safety, analysed using Phoenix…

Certara2023 年 7 月 20 日

Publication

Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

Madin–Darby canine kidney (MDCK) cells are widely used to study epithelial cell functionality. Their low…

Certara2023 年 6 月 28 日

Publication

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers

Discover how no demographic covariates significantly affect granisetron patch PK; no dose adjustment needed, modelled…

Certara2023 年 6 月 26 日

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建模与模拟

Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms

KIC Korea 2026

Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia

Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation

Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study

An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance

Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients

Pharmacokinetic and Bioequivalence Evaluation of Single-Tablet and Separate-Tablet Regimens for Ainuovirine, Lamivudine, and Tenofovir Disoproxil Fumarate in Chinese Healthy Subjects

Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers

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