Bioequivalence Study of Capsules versus Film Tablets Containing Rivaroxaban in Healthy Caucasian Subjects under Fasting and Fed Conditions Publication Bioequivalence Study of Capsules versus Film Tablets Containing Rivaroxaban in Healthy Caucasian Subjects under Fasting and Fed Conditions Discover how capsule and tablet rivaroxaban formulations are bioequivalent with comparable safety, analysed using Phoenix…Certara2023 年 11 月 23 日
Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers Publication Unveiling the Influence of a High-Fat Meal on the Pharmacokinetics of Oral Globalagliatin, A Glucokinase Activator, in Healthy Chinese Volunteers See how high‑fat meals increase globalagliatin exposure by 25–35%, supporting food‑related dosing guidance using Phoenix…Certara2023 年 11 月 20 日
Population pharmacokinetics of rivaroxaban in Chinese deep vein thrombosis patients and the exposure simulation for dosing recommendation. 刊物 Population pharmacokinetics of rivaroxaban in Chinese deep vein thrombosis patients and the exposure simulation for dosing recommendation. Learn how eGFR strongly influences rivaroxaban clearance; PopPK modelling supports renal‑based dose reductions using Phoenix…Certara2023 年 11 月 11 日
Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms Publication Association Study of Esomeprazole Pharmacokinetics and CYP2C19 Gene Polymorphisms Find out how CYP2C19 polymorphisms significantly affect esomeprazole exposure and half‑life, analysed using Phoenix WinNonlin.Certara2023 年 9 月 29 日
Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia Publication Population Pharmacokinetics and Pharmacogenetics Analyses of Dasatinib in Chinese Patients with Chronic Myeloid Leukemia Explore how age increases dasatinib exposure; PopPK modelling supports lower dosing in elderly Chinese CML…Certara2023 年 9 月 19 日
Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation Publication Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation Discover how hemoglobin and eGFR drive imatinib PK variability; PopPK modelling supports caution in renal…Certara2023 年 8 月 25 日
Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study Publication Active Uptake of Oxycodone at Both the Blood-Cerebrospinal Fluid Barrier and The Blood-Brain Barrier without Sex Differences: A Rat Microdialysis Study See how active uptake occurs at both BBB and BCSFB with no sex differences, analysed…Certara2023 年 8 月 23 日
An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance Publication An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance Learn how ARC patients show lower sulbactam exposure and higher clearance, supporting dose increases, analysed…Certara2023 年 8 月 1 日
Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients Publication Evaluation of ceftriaxone pharmacokinetics in hospitalized Egyptian pediatric patients Find out how renal function and hypoalbuminemia alter ceftriaxone PK; current dosing remains appropriate, analysed…Certara2023 年 7 月 24 日