Publication

Population pharmacokinetics of intravenous colistin sulfate and dosage optimization in critically ill patients

Learn how creatinine clearance and ALT drive PK; simulations show need for adjusted dosing using…

Certara2022 年 8 月 29 日

刊物

Pharmacokinetic Study of Nalbuphine in Surgical Patients Undergoing General Anesthesia with Varying Degrees of Liver Dysfunction.

Find out how Liver dysfunction increases nalbuphine half‑life and Vd; PK analysed using Phoenix WinNonlin.

Certara2022 年 7 月 26 日

Publication

Leveraging a Previously Published Population Pharmacokinetic Model to Predict Rivaroxaban Exposure in Real-World Patients

Explore how model predicts population‑level target attainment but large individual variability using Phoenix NLME.

Certara2022 年 7 月 25 日

刊物

Study on pharmacokinetic interactions between SHR2554 and itraconazole in healthy subjects: A single-center, open-label phase I trial.

Discover how itraconazole markedly increases SHR2554 exposure; PK interaction assessed using Phoenix WinNonlin.

Certara2022 年 7 月 16 日

Conference

2026 ACCP Annual Meeting

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Certara2022 年 7 月 15 日

刊物

CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response.

See how CYP2A6 affects exposure; GABRA2 predicts heart‑rate abnormalities using Phoenix NLME.

Certara2022 年 7 月 7 日

Publication

A study to explore the appropriateness of dosing regimen of vancomycin in critically ill patients in a tertiary care unit of India

Learn how weight and creatinine clearance improve prediction; standard dosing insufficient using Phoenix NLME.

Certara2022 年 6 月 30 日

刊物

Evaluation of Pharmacokinetic Interactions Between the New SGLT2 Inhibitor SHR3824 and Valsartan in Healthy Chinese Volunteers.

Find out how co‑administration shows BE‑range PK for both drugs using Phoenix WinNonlin.

Certara2022 年 6 月 28 日

刊物

A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.

Explore how brand and generics show similar exposure but different absorption timing using Phoenix NLME.

Certara2022 年 5 月 21 日

Publication

Comparative clinical study of the pharmacokinetics and bioequivalence of the combined drug Mioreol and the combined use of mono-drugs containing donepezil and memantine

Discover how linear PK up to 600 mg; saturation at 800 mg; PK modelled using…

Certara2022 年 5 月 13 日

沪ICP备2022021526号

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临床药理学

Population pharmacokinetics of intravenous colistin sulfate and dosage optimization in critically ill patients

Pharmacokinetic Study of Nalbuphine in Surgical Patients Undergoing General Anesthesia with Varying Degrees of Liver Dysfunction.

Leveraging a Previously Published Population Pharmacokinetic Model to Predict Rivaroxaban Exposure in Real-World Patients

Study on pharmacokinetic interactions between SHR2554 and itraconazole in healthy subjects: A single-center, open-label phase I trial.

2026 ACCP Annual Meeting

CYP2A6 and GABRA2 Gene Polymorphisms are Associated With Dexmedetomidine Drug Response.

A study to explore the appropriateness of dosing regimen of vancomycin in critically ill patients in a tertiary care unit of India

Evaluation of Pharmacokinetic Interactions Between the New SGLT2 Inhibitor SHR3824 and Valsartan in Healthy Chinese Volunteers.

A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.

Comparative clinical study of the pharmacokinetics and bioequivalence of the combined drug Mioreol and the combined use of mono-drugs containing donepezil and memantine

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