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Conference: 2nd TCE for Autoimmune Disease Summit

日期: 2026 年 10 月 27 - 29 日

地点: The Colonnade Hotel, Boston, MA

Certara is proud to support the 2nd T-Cell Engager for Autoimmune Disease Summit, where discovery, translational, preclinical, and clinical leaders are tackling the field’s biggest challenges: reducing CRS toxicities, improving tissue-selective immune depletion, and expanding T-cell engager (TCE) targets beyond B-cells. As autoimmune TCEs move from oncology-inspired concepts into one of the industry’s most closely watched therapeutic modalities, Certara’s quantitative systems pharmacology (QSP) expertise offers a mechanistic path through the dosing and translational questions shaping this fast-moving field.

Meet Certara at the Summit

Joshua Apgar, PhD

VP, Head of QSP Software

在共同创办Applied BioMath公司之前,Joshua 是勃林格殷格翰制药公司免疫学和炎症部系统生物学小组的首席科学家。他的工作是利用基于物理学的模型:转化体外和体内数据、评估靶点可行性、了解药物作用机制并预测人体剂量。这项工作的最终目标是通过对药物药理学和疾病病理生理学的深入定量研究,减少药物开发后期的损耗。

Joshua 在麻省理工学院获得生物工程博士学位,在那里他从事系统生物学的实验设计工作,研究重点是识别可以用于估算未知参数并揭示信号转导网络复杂机制的可操作性实验。在此之前,Joshua 在 Avaki开发了一个可扩展性极强的软件平台,以支持生命科学和工程领域的高性能计算和企业信息集成。

Scientific Poster

Details coming soon — check back here for Certara’s latest T-cell engager research being presented at the summit.

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