Dr. Apgar is the VP, Head of QSP Software at Certara, and co-founder of Applied BioMath (acquired by Certara in Dec 2023). Prior to this, Josh was a Principal Scientist in the Systems Biology Group of the Department of Immunology and Inflammation at Boehringer Ingelheim Pharmaceuticals. His work leveraged physics-based models to: translate in vitro and in vivo data, assess target feasibility, understand drug mechanism of action, and predict human doses. The ultimate goal of this work was to reduce late stage attrition in drug development through a deep and quantitative interrogation of drug pharmacology and disease pathophysiology.

Joshua 在麻省理工学院获得生物工程博士学位，在那里他从事系统生物学的实验设计工作，研究重点是识别可以用于估算未知参数并揭示信号转导网络复杂机制的可操作性实验。在此之前，Joshua 在 Avaki开发了一个可扩展性极强的软件平台，以支持生命科学和工程领域的高性能计算和企业信息集成。