Intro to Smart In Silico Tools to Aid in Translating In Vitro & In Vivo Studies On-Demand Webinar Intro to Smart In Silico Tools to Aid in Translating In Vitro & In Vivo Studies Safety issues account for about a quarter of the attrition in drug projects, and can…Jim Gallagher2020 年 10 月 5 日
Secondary Intelligence Fact Sheet Secondary Intelligence 预测脱靶风险,简化次级药效学(Secondary Pharmacology)分析,提高药物开发的安全性。Certara2020 年 9 月 4 日
VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays Publication VIVD: Virtual in vitro distribution model for the mechanistic prediction of intracellular concentrations of chemicals in in vitro toxicity assays Danielle Pillsbury2020 年 6 月 28 日
How to Demonstrate Virtual Bioequivalence for Complex Dermal Generic Drugs On-Demand Webinar 如何证明复杂皮肤仿制药的虚拟生物等效性 This webinar will explain how Certara expanded its PBPK Simcyp Simulator to incorporate an extensive…Danielle Pillsbury2020 年 1 月 24 日
Predicting Human Oral Bioavailability: Comparison of In Vivo Animal (Rat- Dog- and Monkey) Studies versus Mechanistic In Vitro In Vivo Extrapolation (IVIVE) Based Predictions Poster Predicting Human Oral Bioavailability: Comparison of In Vivo Animal (Rat- Dog- and Monkey) Studies versus Mechanistic In Vitro In Vivo Extrapolation (IVIVE) Based Predictions Danielle Pillsbury2019 年 11 月 6 日
Fitting PBPK Model Parameters within Simcyp Engine Using Simcyp-R Package Poster Fitting PBPK Model Parameters within Simcyp Engine Using Simcyp-R Package Danielle Pillsbury2019 年 11 月 6 日
Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using the Advanced Dissolution, Absorption and Metabolism (ADAM) model Poster Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using the Advanced Dissolution, Absorption and Metabolism (ADAM) model Danielle Pillsbury2019 年 10 月 22 日
Development of a Permeability-Limited Cardiac Physiologically-Based Pharmacokinetic Model for Predicting Cardiac Exposure Poster Development of a Permeability-Limited Cardiac Physiologically-Based Pharmacokinetic Model for Predicting Cardiac Exposure Danielle Pillsbury2019 年 10 月 17 日
Dosing corrected for species differences in toxicokinetics using PBPK modelling predicts equivalent reactive metabolite burden following acetaminophen overdose Poster Dosing corrected for species differences in toxicokinetics using PBPK modelling predicts equivalent reactive metabolite burden following acetaminophen overdose Danielle Pillsbury2019 年 10 月 17 日