Simplifying Deconvolution
Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…
Certara2014 年 1 月 13 日
The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?
A collaboration between the Consortium for Innovation and Quality in Pharmaceutical Development and the Cardiac…
Certara2014 年 1 月 1 日
Cassette Dosing: Advantages and Challenges
Cassette dosing is a technique primarily used in drug discovery efforts in non-clinical studies to…
Certara2013 年 12 月 16 日
What is GLP (Good Laboratory Practice)?
Good laboratory practice or GLP is a set of principles intended to assure the quality…
Certara2013 年 12 月 9 日
An Evaluation of the Pharmacokinetics of Treprostinil Diethanolamine in Subjects with Hepatic Impairment
Treprostinil diolamine (oral treprostinil) is a prostacyclin analogue under evaluation for the treatment for pulmonary…
Certara2013 年 12 月 1 日
Modeling of Pharmacokinetic Systems Using Stochastic Deconvolution
In environments where complete mechanistic knowledge of the system dynamics is not available, a synergy…
Certara2013 年 12 月 1 日
Understanding Steady State Pharmacokinetics
Register for our July 10 webinar and discover fast, flexible, frictionless PK/PD workflows with Phoenix…
Certara2013 年 11 月 25 日
Absence of Pharmacokinetic Drug-drug Interaction of Pertuzumab with Trastuzumab and Docetaxel
Pertuzumab is a novel antihuman epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody. Combined…
Certara2013 年 11 月 24 日
Phoenix WinNonlin: A State of the Art Software Tool for Pre-clinical PK and TK Analysis
Are you currently using Excel for PK/TK analysis? Phoenix WinNonlin streamlines analyses and generates all…
Certara2013 年 11 月 21 日
What is Identifiability?
Developing models for pharmacokinetic or pharmacodynamic data requires creativity, patience, and hard work. Sometimes that…
Certara2013 年 11 月 18 日
