Modeling and Simulation - PK/PD Archives | 第 24 页，共 38 页

Publication

Population Pharmacokinetics of Azithromycin in Whole Blood, Peripheral Blood Mononuclear Cells, and Polymorphonuclear Cells in Healthy Adults

Azithromycin's extensive distribution to proinflammatory cells, including peripheral blood mononuclear cells (PBMCs) and polymorphonuclear cells…

Certara2014 年 3 月 5 日

Publication

Impact of Electrocardiographic Data Quality on Moxifloxacin Response in Thorough QT/QTc Studies

Thorough QT studies are typically conducted for drugs with systemic bioavailability and include a positive…

Certara2014 年 3 月 1 日

Publication

Population Pharmacokinetic Analysis of Axitinib in Healthy Volunteers

Axitinib is a potent and selective second generation inhibitor of vascular endothelial growth factor receptors…

Certara2014 年 2 月 21 日

Publication

A Model-based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-malignant Pain

Pain is a major symptom in many medical conditions which can be relieved thanks to…

Certara2014 年 2 月 13 日

Publication

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Certara2014 年 2 月 10 日

Knowledge Base

Simplifying Deconvolution

Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…

Certara2014 年 1 月 13 日

刊物

The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?

A collaboration between the Consortium for Innovation and Quality in Pharmaceutical Development and the Cardiac…

Certara2014 年 1 月 1 日

Knowledge Base

Cassette Dosing: Advantages and Challenges

Cassette dosing is a technique primarily used in drug discovery efforts in non-clinical studies to…

Certara2013 年 12 月 16 日

Blog Knowledge Base

What is GLP (Good Laboratory Practice)?

Good laboratory practice or GLP is a set of principles intended to assure the quality…

Certara2013 年 12 月 9 日

Publication

An Evaluation of the Pharmacokinetics of Treprostinil Diethanolamine in Subjects with Hepatic Impairment

Treprostinil diolamine (oral treprostinil) is a prostacyclin analogue under evaluation for the treatment for pulmonary…

Certara2013 年 12 月 1 日

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Modeling and Simulation – PK/PD

Population Pharmacokinetics of Azithromycin in Whole Blood, Peripheral Blood Mononuclear Cells, and Polymorphonuclear Cells in Healthy Adults

Impact of Electrocardiographic Data Quality on Moxifloxacin Response in Thorough QT/QTc Studies

Population Pharmacokinetic Analysis of Axitinib in Healthy Volunteers

A Model-based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-malignant Pain

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Simplifying Deconvolution

The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?

Cassette Dosing: Advantages and Challenges

What is GLP (Good Laboratory Practice)?

An Evaluation of the Pharmacokinetics of Treprostinil Diethanolamine in Subjects with Hepatic Impairment

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