Publication

Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients

See how standard vancomycin dosing is insufficient for pediatric liver‑transplant patients, requiring higher or more…

Certara2021 年 10 月 6 日

Case Study

Bridging Formulations of Quetiapine for Children with Schizophrenia or Bipolar Disorder

Quetiapine is an atypical antipsychotic for treating schizophrenia, bipolar depression, bipolar mania that helps to…

Certara2021 年 8 月 26 日

Case Study

Aripiprazole lauroxil: PBPK for Dosing Regimen and DDI Identification

Aripiprazole lauroxil (Aristada®) was approved by the FDA for treating schizophrenia in adults in October…

Certara2021 年 8 月 12 日

Publication

Population Pharmacokinetics of Diethylcarbamazine in Patients with Lymphatic Filariasis and Healthy Individuals

Find out how body‑weight and sex effects on DEC PK in filariasis patients, supporting improved…

Certara2021 年 7 月 26 日

Publication

Cystatin C and/or creatinine-based estimated glomerular filtration rate for prediction of vancomycin clearance in long-stay critically ill patients with persistent inflammation, immunosuppression and catabolism syndrome (PICS): a population pharmacokinetics analysis

Learn how cystatin‑C improves vancomycin clearance prediction in PICS patients, reducing variability and preventing supratherapeutic…

Certara2021 年 3 月 16 日

Publication

Population Pharmacokinetics and Dosage Optimization of Linezolid in Critically Ill Pediatric Patients

Explore how key covariates and showed higher‑frequency dosing improves linezolid target attainment in critically ill…

Certara2021 年 2 月 8 日

Fact Sheet

Phoenix WinNonlin

Certara2020 年 6 月 22 日

White Paper

利用 QSP 优化免疫肿瘤药物发现与开发

A Quantitative Systems Pharmacology (QSP) approach for developing combination immune-oncology therapies can be used to…

Certara2019 年 6 月 19 日

Brochure

Pirana 建模工作平台

Pirana is a flexible and extendible modeling workbench with an intuitive graphical user interface for…

Certara2019 年 5 月 28 日

Blog

勘测全球范围监管申请建模与模拟的现状

Analogous to how a geologist surveys the “lay of the land” to determine if oil…

Certara2018 年 2 月 16 日

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Population Pharmacokinetics and Dosing Optimization of Vancomycin in Pediatric Liver Transplant Recipients

Bridging Formulations of Quetiapine for Children with Schizophrenia or Bipolar Disorder

Aripiprazole lauroxil: PBPK for Dosing Regimen and DDI Identification

Population Pharmacokinetics of Diethylcarbamazine in Patients with Lymphatic Filariasis and Healthy Individuals

Cystatin C and/or creatinine-based estimated glomerular filtration rate for prediction of vancomycin clearance in long-stay critically ill patients with persistent inflammation, immunosuppression and catabolism syndrome (PICS): a population pharmacokinetics analysis

Population Pharmacokinetics and Dosage Optimization of Linezolid in Critically Ill Pediatric Patients

Phoenix WinNonlin

利用 QSP 优化免疫肿瘤药物发现与开发

Pirana 建模工作平台

勘测全球范围监管申请建模与模拟的现状

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