In Vivo Indices of Enzyme Activity—The Effect of Renal Impairment on the Assessment of CYP2D6 Activity Publication In Vivo Indices of Enzyme Activity—The Effect of Renal Impairment on the Assessment of CYP2D6 Activity Urinary drug metabolite ratios and urinary recoveries of metabolites, have been used to assess specific…Certara1999 年 6 月 1 日
The Determination of Drug Metabolizing Enzyme Activity In Vivo: Pharmacokinetics and Statistical Issues Publication The Determination of Drug Metabolizing Enzyme Activity In Vivo: Pharmacokinetics and Statistical Issues Probe substrates for various isoforms of cytochrome P450 and other drug-metabolizing enzymes are now widely…Certara1998 年 12 月 1 日
Caffeine Metabolic Ratios as Markers of Enzyme Activity: A Theoretical Assessment Publication Caffeine Metabolic Ratios as Markers of Enzyme Activity: A Theoretical Assessment At least six urinary metabolite ratios of caffeine have been proposed as probes for in…Certara1996 年 4 月 1 日