Enhancing clinical trials with real-world evidence in pregnancy research Blog Enhancing clinical trials with real-world evidence in pregnancy research Learn how real-world evidence improves clinical trials in pregnancy by enhancing safety data, trial design,…Certara2026 年 6 月 26 日
Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies Poster 将内源性配体竞争纳入治疗性单克隆抗体的机制全身 PBPK 模型 Discover how endogenous ligand competition was incorporated into a whole-body PBPK model to improve prediction…Certara2026 年 6 月 23 日
Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Poster Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Learn how Certara's IO Simulator was used to predict efficacy, cytokine release syndrome risk, and…Certara2026 年 6 月 23 日
Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Poster Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Discover how Quantitative Systems Pharmacology (QSP) was used to predict cytokine release syndrome risk and…Certara2026 年 6 月 23 日
Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling Poster Machine Learning-Based Covariate Selection for Population Pharmacokinetic Modeling Authors: Ibtissem Rebai (Certara), Stephen Duffull (Certara), Ayman Akil (Certara), Anna Largajolli (Certara), Floris Fauchet…Certara2026 年 6 月 22 日
Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices Poster Shaping the future of AI/ML in pharmacometrics through collaboration, education and best practices Discover how the AI/ML Special Interest Group is advancing responsible artificial intelligence in pharmacometrics through…Certara2026 年 6 月 22 日
Machine Learning based drug renal clearance predictor development and application Poster Machine Learning based drug renal clearance predictor development and application A machine learning QSAR model predicts human renal clearance from simple, easy-to-obtain inputs and sharpens…Certara2026 年 6 月 22 日
Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization Poster Accelerating QSP Virtual Population Generation Through Active Learning and Bayesian Optimization Discover how active learning and Bayesian optimization improve virtual population generation for quantitative systems pharmacology…Certara2026 年 6 月 18 日
Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development Poster Mechanistic QSP Modeling to Support KIT Inhibitor Dose Selection, Biomarker Strategy, and Clinical Development Discover how a mechanistic quantitative systems pharmacology (QSP) model predicts mast cell inhibition and depletion…Certara2026 年 6 月 16 日
Data, Models, and Modalities: Key Themes from the Certainty 2026 Discovery UGM Blog Data, Models, and Modalities: Key Themes from the Certainty 2026 Discovery UGM A recap of the Certainty 2026 Discovery UGM in Boston, covering the top themes from…Certara2026 年 6 月 15 日