Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Certara2024 年 10 月 30 日
Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio Publication Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio Explore how milk pH and fat content influence drug milk-to-plasma ratio predictions and inform lactation…Certara2024 年 10 月 25 日
16th Annual World ADC London 2026 Conference 16th Annual World ADC London 2026 Certara2024 年 10 月 11 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Certara2024 年 9 月 18 日
A tutorial on PBPK approaches in lactation research Publication A tutorial on PBPK approaches in lactation research Learn how physiologically based pharmacokinetic modeling can support drug transfer and infant exposure predictions during…Certara2024 年 9 月 16 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Certara2024 年 9 月 16 日
Application of physiologically based pharmacokinetic modeling of novel drugs approved by the U.S. food and drug administration Publication 美国 FDA 批准的新型药物应用基于生理的药代动力学模型应用 The article from the European Journal of Pharmaceutical Sciences reviews the role of Physiologically Based…Certara2024 年 9 月 1 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator Publication 预测涉及抑制作用的 CYP 介导的 DDIs:满足 Simcyp Simulator 系统鉴定要求的方法 The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) Publication Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…Certara2024 年 8 月 26 日
Certara’s MIDD Oncology Capabilities Video Certara 在 MIDD 领域的肿瘤学解决能力 Improve Oncology Study Decisions with Certara's MIDD Team Transcript: The pace of oncology drug…Certara2024 年 8 月 7 日