CODEX Clinical Outcomes Databases Hidradenitis Suppurativa (HS)
Explore Certara's CODEX Hidradenitis Suppurativa database ~43 studies with key efficiency and safety endpoints (HiSCR50,…
Danielle Pillsbury2026 年 9 月 25 日
CODEX Clinical Outcomes Databases Chronic Heart Failure (CHF)
Explore Certara's CODEX Chronic Heart Failure database ~200 studies with key efficiency and safety endpoints…
Certara2026 年 9 月 25 日
Modeling effective doses of therapeutic antibodies targeting clustered surface receptors
Discover how semi-mechanistic PK/receptor-occupancy modeling reveals that lower, subcutaneous doses, not maximum tolerated doses, optimize…
Danielle Pillsbury2026 年 9 月 23 日
Model-Informed Strategies for ADC Development
Explore how model informed drug development can help ADC developers optimize dosing, reduce uncertainty, strengthen…
Danielle Pillsbury2026 年 9 月 22 日
When EV Dose Is Not What It Seems: Quantitative Mismatch Between Particle Number- and Protein-Based Dosing
Research shows that particle- and protein-based extracellular vesicle dosing are not interchangeable, supporting a multidimensional…
Certara2026 年 9 月 18 日
Semi-Mechanistic Joint Population Pharmacokinetic Modeling of the Novel Antituberculosis Drug Sorfequiline and Its Metabolite M3 in Healthy Volunteers
A semi-mechanistic population PK model characterizes sorfequiline and its active M3 metabolite to support DDI…
Certara2026 年 9 月 18 日
External Data Accelerator: Your standards-first team and technology for conformant vendor data
Our tech-enabled team embeds standards and validation from day one, so your data lands clean,…
Certara2026 年 9 月 15 日
Pharmacometric Analysis of Givinostat to Support Individualized Dosing Recommendations in Pediatric Patients with Duchenne Muscular Dystrophy
Pharmacometric modeling of givinostat in pediatric DMD supported a simplified 4-band weight-based dosing regimen without…
Certara2026 年 9 月 14 日
Beyond NAMs versus animal models: Context of use as the governing framework for integrated nonclinical strategies in drug development
A new paper argues context of use, not NAMs-versus-animals, should govern nonclinical strategy in drug…
Danielle Pillsbury2026 年 9 月 9 日
