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基因疗法模型包

Pre-built library of validated QSP models for mRNA and siRNA

QSP models for gene therapies

The Gene Therapy Model Pack is a pre-built model pack used with Certara IQ™, and it empowers researchers with advanced tools to simulate and predict outcomes for gene therapies. Its applications span from intracellular protein expression to extracellular protein delivery, ensuring comprehensive support for therapeutic development.

Includes models for both mRNA and siRNA therapies

Covers in vitro and in vivo scenarios for intracellular and extracellular protein expression

Features pharmacology diagrams and parameter sets with default values

Model diagrams and parameters

Each model in the Gene Therapy Model Pack includes a mechanism of action diagram and a pharmacology diagram with model parameters and their nominal values. Each model in Certara IQ has a unique set of parameters, based on the model pharmacology and number of compartments. In the app, each parameter contains a default value based on expansive literature searches and references.

QSP model diagram for gene therapy

Created in Biorender

Explore other Certara IQ QSP model packs

In addition to the Gene Therapy model pack, Certara IQ offers several libraries of monospecific and bispecific, single-compartment and multicompartment models covering common pharmacologies.

Download the Gene Therapy model pack

Discover how using the Gene Therapy Model Pack can help tackle your unique gene therapy development challenges.

Gain access to 8 comprehensive models for gene therapy

Leverage in-depth parameters and pharmacology diagrams

Enhance therapeutic predictions with cutting-edge tools

Certara IQ Support

Have questions about how model pack libraries accelerate modeling in Certara IQ?

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