Population Pharmacokinetics of Olmesartan Following Oral Administration of Its Prodrug, Olmesartan Medoxomil: In Healthy Volunteers and Hypertensive Patients Publication Population Pharmacokinetics of Olmesartan Following Oral Administration of Its Prodrug, Olmesartan Medoxomil: In Healthy Volunteers and Hypertensive Patients Olmesartan medoxomil (CS-866) is a new orally active angiotensin II receptor antagonist that is highly…Certara2005 年 1 月 1 日
The Use of Clinical Trial Simulation to Support Dose Selection: Application to Development of a New Treatment for Chronic Neuropathic Pain Publication The Use of Clinical Trial Simulation to Support Dose Selection: Application to Development of a New Treatment for Chronic Neuropathic Pain Pregabalin is being evaluated for the treatment of neuropathic pain. Two phase 2 studies were…Certara2003 年 11 月 1 日
Pharmacokinetics of Melagatran and the Effect on Ex Vivo Coagulation Time in Orthopedic Surgery Patients Receiving Subcutaneous Melagatran and Oral Ximelagatran: A Population Model Analysis Publication Pharmacokinetics of Melagatran and the Effect on Ex Vivo Coagulation Time in Orthopedic Surgery Patients Receiving Subcutaneous Melagatran and Oral Ximelagatran: A Population Model Analysis Ximelagatran, an oral direct thrombin inhibitor, is rapidly bioconverted to melagatran, its active form. The…Certara2003 年 1 月 1 日