A glimpse into the future of model-informed drug discovery and development Publication A glimpse into the future of model-informed drug discovery and development Explore the future of Model-Informed Drug Development (MIDD), including advances in pharmacometrics, PBPK, QSP, precision…Certara2026 年 8 月 28 日
Refinement of Operating Characteristics for Model-Based TGI Metrics Decision Support to Ungate a Pivotal Trial in Oncology Publication Refinement of Operating Characteristics for Model-Based TGI Metrics Decision Support to Ungate a Pivotal Trial in Oncology Explore how model-based tumor growth inhibition metrics can support earlier Go/No-Go decisions and pivotal trial…Certara2026 年 8 月 28 日
A model-informed approach to radioligand therapy dosing under Project Optimus Blog A model-informed approach to radioligand therapy dosing under Project Optimus Explore how targeted radionuclide therapy dosing uses QSP, biologically effective dose (BED), and exposure-response modeling…Hunter Stephens, PhD2026 年 8 月 13 日
CHI Webinar: From Dosimetry to Dose Decisions How Clinical Pharmacology and Model-Informed Approaches Are Shaping TRT Development Webinar CHI Webinar: From Dosimetry to Dose Decisions How Clinical Pharmacology and Model-Informed Approaches Are Shaping TRT Development Hunter Stephens, PhD2026 年 7 月 17 日
Dosimetry for radiopharmaceutical therapy: From measurement to dose justification Blog Dosimetry for radiopharmaceutical therapy: From measurement to dose justification Why dosimetry for radiopharmaceutical therapy needs more than absorbed dose. How BED, radiation dosimetry &…Hunter Stephens, PhD2026 年 7 月 7 日
Enhancing clinical trials with real-world evidence in pregnancy research Blog Enhancing clinical trials with real-world evidence in pregnancy research Learn how real-world evidence improves clinical trials in pregnancy by enhancing safety data, trial design,…Alekhya Lavu, PhD, PharmD2026 年 6 月 26 日
Integrating Endogenous Ligand Competition into a Mechanistic Whole-Body PBPK Model of Therapeutic Monoclonal Antibodies Poster 将内源性配体竞争纳入治疗性单克隆抗体的机制全身 PBPK 模型 Discover how endogenous ligand competition was incorporated into a whole-body PBPK model to improve prediction…Certara2026 年 6 月 23 日
Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Poster Application of IO Simulator in Immuno-Oncology Combination Therapy: A Small Cell Lung Cancer Case Study Learn how Certara's IO Simulator was used to predict efficacy, cytokine release syndrome risk, and…Certara2026 年 6 月 23 日
Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Poster Mechanistic Modelling of CRS in T-cell Engagers – An Application for Blinatumomab Discover how Quantitative Systems Pharmacology (QSP) was used to predict cytokine release syndrome risk and…Certara2026 年 6 月 23 日