Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Poster Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Certara2019 年 10 月 16 日
Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Poster Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Certara2019 年 10 月 15 日
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Certara2019 年 10 月 15 日
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Certara2019 年 10 月 15 日
Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Certara2019 年 10 月 11 日
Physiological verification of a geriatric population using the Simcyp R package Poster Physiological verification of a geriatric population using the Simcyp R package Certara2019 年 10 月 11 日
Estimation of Effective pKa of Bicarbonate Buffer Poster Estimation of Effective pKa of Bicarbonate Buffer Certara2019 年 10 月 11 日
Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics Poster Quantification of Human Blood-Brain Barrier Transporters in Health and in Dementia by Global and Targeted Proteomics Certara2019 年 10 月 11 日
The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver Poster The Molecular Stethoscope: RNA of Drug Metabolising Enzymes in Circulating Vesicles Correlates with their Specific Protein Content in the Liver Certara2019 年 10 月 11 日
Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds Poster Propofol: A Tail of Drug Disposition and Dynamics in Different Dog Breeds Certara2019 年 10 月 11 日
