Certara Products - Simcyp Archives | 第 4 页，共 22 页

Case Study

Using PBPK Models to Predict Effects of Hepatic Impairment & DDI in Olanzapine/Samidorphan Combination Therapy

Olanzapine is an effective antipsychotic medication used to treat schizophrenia, a disease that affects about…

Certara2022 年 10 月 31 日

Blog

为何应在开始临床研究前选择药物制剂

药物开发者常急于推进发现流程以进入人体试验。Most are…

Certara2022 年 10 月 28 日

Conference

ACCP 年度会议

– – Booth

Certara2022 年 7 月 15 日

Brochure

Simcyp™ Discovery Simulator

Tailored for discovery and translational scientists, Simcyp Discovery Simulator is an intuitive software that delivers…

Certara2022 年 7 月 14 日

Case Study

Simcyp Simulator 有助于优化成人和青少年孤儿病患者的用药剂量

全世界约有 400,000 名先天性肾上腺增生症（CAH）患者。Current therapy for CAH uses a…

Certara2022 年 6 月 6 日

Case Study

PBPK Modeling in Adults Enables DDI Risk Assessment in Children with SMA

In 2020, the US FDA approved Risdiplam (Evrysdi®) as the first orally administered drug to…

Certara2022 年 6 月 2 日

Case Study

PBPK Model Informs Antibody-Drug Conjugate Label for DDIs Without Clinical Trials

Genentech was developing polatuzumab vedotin (Polivy), an anti-CD79b-vc-monomethyl auristatin E (MMAE) antibody-drug conjugate (ADC) to…

Certara2022 年 4 月 11 日

Video

Certara Simcyp Simulator 演示

The Simcyp PBPK Simulator is the industry leader and most widely adopted platform for PBPK…

Certara2022 年 1 月 20 日

Case Study

使用 Simcyp Simulator 确定 Guanfacine 在儿童中的药物相互作用风险

Guanfacine (Intuniv® XR) extended release (GXR) is an orally administered, selective alpha2A-adrenergic receptor agonist, non-stimulant…

Certara2021 年 8 月 26 日

Case Study

Using a PBPK-PD Receptor Occupancy Model to Determine the Optimal Dose of Radiprodil for Neonates

Radiprodil is a selective allosteric modulator of the NR2B N-methyl-D-aspartate receptor GluN2B-NMDA that was being…

Certara2021 年 8 月 26 日

Certara Products – Simcyp

Using PBPK Models to Predict Effects of Hepatic Impairment & DDI in Olanzapine/Samidorphan Combination Therapy

为何应在开始临床研究前选择药物制剂

ACCP 年度会议

Simcyp™ Discovery Simulator

Simcyp Simulator 有助于优化成人和青少年孤儿病患者的用药剂量

PBPK Modeling in Adults Enables DDI Risk Assessment in Children with SMA

PBPK Model Informs Antibody-Drug Conjugate Label for DDIs Without Clinical Trials

Certara Simcyp Simulator 演示

使用 Simcyp Simulator 确定 Guanfacine 在儿童中的药物相互作用风险

Using a PBPK-PD Receptor Occupancy Model to Determine the Optimal Dose of Radiprodil for Neonates

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