Towards Virtual Exposure Assessment of Dermally Applied Drugs – PBPK Model of Buprenorphine Transdermal Patches Poster Towards Virtual Exposure Assessment of Dermally Applied Drugs – PBPK Model of Buprenorphine Transdermal Patches Certara2019 年 8 月 29 日
Integration of physicochemical product characteristics within a mechanistic dermal PBPK model to support virtual bioequivalence evaluation of topical drug products: A case study with acyclovir topical creams Poster Integration of physicochemical product characteristics within a mechanistic dermal PBPK model to support virtual bioequivalence evaluation of topical drug products: A case study with acyclovir topical creams Certara2019 年 8 月 29 日
Formulations can have an impact on intestinal drug-drug interactions: A PBPK study using oxybutynin as a model drug Poster Formulations can have an impact on intestinal drug-drug interactions: A PBPK study using oxybutynin as a model drug Certara2019 年 8 月 29 日
Effect of Multiple Drugs Interacting with the hERG Channel – In Vitro Study Poster Effect of Multiple Drugs Interacting with the hERG Channel – In Vitro Study Certara2019 年 8 月 29 日
Performance Verification of V17 updates to Sim Japanese Population: a focus on CYP abundance Poster Performance Verification of V17 updates to Sim Japanese Population: a focus on CYP abundance Certara2019 年 8 月 29 日
VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Poster VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Certara2019 年 8 月 29 日
On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Poster On Early Paediatric Study Design: 在 Simcyp Simulator 中使用 PBPK 方法计算样本量 Certara2019 年 8 月 29 日
Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Certara2019 年 8 月 29 日
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Certara2019 年 8 月 28 日
Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Poster Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Certara2019 年 8 月 28 日