Modeling and Simulation - PK/PD Archives | 第 42 页，共 47 页

Publication

Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients

TBR-652 is a novel CCR5 antagonist with potent in vitro anti-HIV activity. The objective of…

Certara2011 年 4 月 12 日

Blog Knowledge Base

What to Do with Those BLQs!

BLQ values are like those pimples we used to get as teenagers. They…

Certara2011 年 4 月 6 日

Blog Knowledge Base

The Difference Between Vd and Vss

There are many terms used to represent volume of distribution, but two common ones are…

Certara2011 年 3 月 31 日

知识库

What is Shrinkage?

In 2007, Mats Karlsson and Radojka Savic published a perspective in Clinical Pharmacology & Therapeutics…

Certara2011 年 3 月 29 日

知识库

Is a Monte Carlo Simulation an Exotic Drink?

The term “Monte Carlo simulation” is often used in the modeling and simulation literature with…

Certara2011 年 3 月 21 日

知识库

What is WinNonlin?

A reader suggested that I write a similar post about WinNonlin. Great idea! Thank you!…

Certara2011 年 3 月 16 日

知识库

个体 PK 和群体 PK 有什么区别？

药代动力学分析通常分为两个领域...... "PK "和 "群体 PK"。Sometimes the…

Certara2011 年 3 月 14 日

知识库

Blood or Plasma? Which Should You Assay for Drug Concentration?

Explore blood vs. plasma drug concentration assays. Learn their differences, relationships, and impact on accurate…

Certara2011 年 2 月 19 日

Blog Knowledge Base

Why Should You Evaluate Dose Proportionality?

Dose proportionality is a common phrase used pharmacokinetics. Early in the pre-clinical development process, we…

Certara2011 年 2 月 17 日

知识库

What is the Difference Between PK and TK?

Explore the key differences between pharmacokinetics (PK) and toxicokinetics (TK), their roles in drug development,…

Certara2011 年 2 月 15 日

Modeling and Simulation – PK/PD

Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients

What to Do with Those BLQs!

The Difference Between Vd and Vss

What is Shrinkage?

Is a Monte Carlo Simulation an Exotic Drink?

What is WinNonlin?

个体 PK 和群体 PK 有什么区别？

Blood or Plasma? Which Should You Assay for Drug Concentration?

Why Should You Evaluate Dose Proportionality?

What is the Difference Between PK and TK?

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