Modeling and Simulation - PK/PD Archives | 第 23 页，共 37 页

Publication

Population Pharmacokinetic Analysis of Axitinib in Healthy Volunteers

Axitinib is a potent and selective second generation inhibitor of vascular endothelial growth factor receptors…

Danielle Pillsbury2014 年 2 月 21 日

Publication

A Model-based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-malignant Pain

Pain is a major symptom in many medical conditions which can be relieved thanks to…

Danielle Pillsbury2014 年 2 月 13 日

Publication

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Danielle Pillsbury2014 年 2 月 10 日

Knowledge Base

Simplifying Deconvolution

Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…

Nathan Teuscher2014 年 1 月 13 日

刊物

The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?

A collaboration between the Consortium for Innovation and Quality in Pharmaceutical Development and the Cardiac…

Danielle Pillsbury2014 年 1 月 1 日

Knowledge Base

Cassette Dosing: Advantages and Challenges

Cassette dosing is a technique primarily used in drug discovery efforts in non-clinical studies to…

Nathan Teuscher2013 年 12 月 16 日

Blog Knowledge Base

What is GLP (Good Laboratory Practice)?

Good laboratory practice or GLP is a set of principles intended to assure the quality…

Certara2013 年 12 月 9 日

Publication

An Evaluation of the Pharmacokinetics of Treprostinil Diethanolamine in Subjects with Hepatic Impairment

Treprostinil diolamine (oral treprostinil) is a prostacyclin analogue under evaluation for the treatment for pulmonary…

Danielle Pillsbury2013 年 12 月 1 日

Publication

Modeling of Pharmacokinetic Systems Using Stochastic Deconvolution

In environments where complete mechanistic knowledge of the system dynamics is not available, a synergy…

Danielle Pillsbury2013 年 12 月 1 日

Blog Knowledge Base

Understanding Steady State Pharmacokinetics

“Steady state” is an important term in pharmacokinetics, but it can often seem a bit…

Certara2013 年 11 月 25 日

Modeling and Simulation – PK/PD

Population Pharmacokinetic Analysis of Axitinib in Healthy Volunteers

A Model-based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-malignant Pain

Clinical Population Pharmacokinetics and Toxicodynamics of Linezolid

Simplifying Deconvolution

The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study?

Cassette Dosing: Advantages and Challenges

What is GLP (Good Laboratory Practice)?

An Evaluation of the Pharmacokinetics of Treprostinil Diethanolamine in Subjects with Hepatic Impairment

Modeling of Pharmacokinetic Systems Using Stochastic Deconvolution

Understanding Steady State Pharmacokinetics

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