Modeling and Simulation - PK/PD Archives | 第 14 页，共 37 页 | Certara

Publication

A Study to Examine the Relationship Between Metritis Severity and Depletion of Oxytetracycline in Plasma and Milk after Intrauterine Infusion

Metritis is a frequent problem in postpartum dairy cows. Intrauterine therapy with the antimicrobial oxytetracycline…

Danielle Pillsbury2016 年 10 月 1 日

Publication

Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains

Danielle Pillsbury2016 年 10 月 1 日

Blog

Arming Adherence-based Drug Development with Pharmacometrics

The time is right to explore how sensor-enabled digital adherence monitoring systems can benefit patients,…

Certara2016 年 9 月 12 日

Brochure

Phoenix NLME，面向当今科学家的现代 PK/PD 建模软件

Phoenix NLME 是一款用户友好、易于学习的 PK/PD 建模软件。Built from the…

Danielle Pillsbury2016 年 9 月 12 日

Brochure

罕见病和孤儿药开发

There are 7,000 rare diseases impacting 350 million patients worldwide, yet only 300 of these…

Danielle Pillsbury2016 年 8 月 3 日

Publication

Population Pharmacokinetics of Bevacizumab in Cancer Patients with External Validation

Danielle Pillsbury2016 年 8 月 1 日

Publication

Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-cultured Hepatocytes, Mechanistic Modeling, and Simulation

Danielle Pillsbury2016 年 8 月 1 日

White Paper

基于模型的荟萃分析（MBMA）：创新方法的时代来临了

MBMA integrates internal and external drug development data to inform proprietary commercial and R&D decisions.…

Danielle Pillsbury2016 年 7 月 14 日

Publication

Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients with Renal Impairment

Avibactam is a non-β-lactam β-lactamase inhibitor intended for use as a fixed-dose combination with ceftazidime…

Danielle Pillsbury2016 年 7 月 12 日

Publication

More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-mediated Clearances

Rosuvastatin is a substrate of choice in clinical studies of organic anion-transporting polypeptide (OATP)1B1- and…

Danielle Pillsbury2016 年 7 月 1 日

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