Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody
The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…
Certara2024 年 11 月 4 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women
The article titled "Using PBPK modeling to supplement clinical data and support the safe and…
Certara2024 年 10 月 30 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk
The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…
Certara2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research
The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…
Certara2024 年 9 月 16 日
Application of physiologically based pharmacokinetic modeling of novel drugs approved by the U.S. food and drug administration
The article from the European Journal of Pharmaceutical Sciences reviews the role of Physiologically Based…
Certara2024 年 9 月 1 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…
Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…
Certara2024 年 8 月 26 日
Certara’s MIDD Oncology Capabilities
Improve Oncology Study Decisions with Certara's MIDD Team Transcript: The pace of oncology drug…
Certara2024 年 8 月 7 日
A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator
This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…
Certara2024 年 7 月 24 日
