Optimize Immuno-oncology Drug Discovery and Development Using QSP White Paper 利用 QSP 优化免疫肿瘤药物发现与开发 A Quantitative Systems Pharmacology (QSP) approach for developing combination immune-oncology therapies can be used to…Certara2019 年 6 月 19 日
Pirana Modeling Workbench Brochure Pirana 建模工作平台 Pirana is a flexible and extendible modeling workbench with an intuitive graphical user interface for…Certara2019 年 5 月 28 日
Precision Dosing in Clinical Medicine: Present and Future Publication Precision Dosing in Clinical Medicine: Present and Future Certara2018 年 7 月 20 日
Apixaban for treatment of venous thromboembolism (VTEtx): Use of MBMA to support Phase 3 dose selection and beyond Publication Apixaban for treatment of venous thromboembolism (VTEtx): Use of MBMA to support Phase 3 dose selection and beyond Apixaban is an orally available, direct, selective inhibitor of the coagulation factor Xa that reversibly…Certara2018 年 6 月 2 日
Optimization of Intestinal Microsomal Preparation in the Rat: A Systematic Approach to Assess the Influence of Various Methodologies on Metabolic Activity and Scaling Factors Publication Optimization of Intestinal Microsomal Preparation in the Rat: A Systematic Approach to Assess the Influence of Various Methodologies on Metabolic Activity and Scaling Factors Certara2017 年 4 月 1 日
The Model-informed Precision Dosing Revolution Is Coming Blog The Model-informed Precision Dosing Revolution Is Coming Modeling and simulation (M&S) has been widely accepted and adopted by biopharmaceutical companies and global…Certara2017 年 3 月 7 日
Biopharmaceutics Data Management System for Anonymized Data Sharing and Curation: First Application with Orbito IMI Project Publication Biopharmaceutics Data Management System for Anonymized Data Sharing and Curation: First Application with Orbito IMI Project Certara2017 年 3 月 1 日
Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update Publication Prediction of Liver Volume—A Population-based Approach to Meta-analysis of Pediatric, Adult, and Geriatric Populations—An Update —Certara2017 年 3 月 1 日
The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism Publication The Absorption Kinetics of Ketoconazole Plays a Major Role in Explaining the Reported Variability in the Level of Interaction with Midazolam: Interplay Between Formulation and Inhibition of Gut Wall and Liver Metabolism Certara2017 年 2 月 1 日
The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves Publication The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…Certara2016 年 12 月 1 日