Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio Publication Impact of Milk pH and Fat Content on the Prediction of Milk-to-Plasma Ratio Explore how milk pH and fat content influence drug milk-to-plasma ratio predictions and inform lactation…Certara2024 年 10 月 25 日
16th Annual World ADC London 2026 Conference 16th Annual World ADC London 2026 Certara2024 年 10 月 11 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Certara2024 年 9 月 18 日
A tutorial on PBPK approaches in lactation research Publication A tutorial on PBPK approaches in lactation research Learn how physiologically based pharmacokinetic modeling can support drug transfer and infant exposure predictions during…Certara2024 年 9 月 16 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Certara2024 年 9 月 16 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator Publication 预测涉及抑制作用的 CYP 介导的 DDIs:满足 Simcyp Simulator 系统鉴定要求的方法 The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) Publication Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…Certara2024 年 8 月 26 日
临床开发计划如何帮助药物项目? 博客 临床开发计划如何帮助药物项目? How important is a clinical development plan? Your biotechnology start-up’s candidate asset has an intriguing…Certara2024 年 7 月 26 日
A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator Publication 在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南 This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…Certara2024 年 7 月 24 日