Why Clinical Pharmacology & Pharmacometrics Should Collaborate
A symbiosis between a modeler and a trialist is often required to develop a model-informed…
Certara2024 年 11 月 8 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody
The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…
Certara2024 年 11 月 4 日
How Generative AI is Unlocking Insights to Expand Drug Development with Dr. Chris Bouton
From accelerating therapeutic innovation to breaking down data silos, this episode dives into how AI…
Certara2024 年 10 月 30 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women
The article titled "Using PBPK modeling to supplement clinical data and support the safe and…
Certara2024 年 10 月 30 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk
The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…
Certara2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research
The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…
Certara2024 年 9 月 16 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…
Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…
Certara2024 年 8 月 26 日
