Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Certara2024 年 10 月 30 日
16th Annual World ADC London 2026 Conference 16th Annual World ADC London 2026 Certara2024 年 10 月 11 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Certara2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Certara2024 年 9 月 16 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator Publication 预测涉及抑制作用的 CYP 介导的 DDIs:满足 Simcyp Simulator 系统鉴定要求的方法 The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) Publication Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…Certara2024 年 8 月 26 日
临床开发计划如何帮助药物项目? 博客 临床开发计划如何帮助药物项目? How important is a clinical development plan? Your biotechnology start-up’s candidate asset has an intriguing…Certara2024 年 7 月 26 日
A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator Publication 在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南 This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…Certara2024 年 7 月 24 日
A literature review of drug transport mechanisms during lactation Publication A literature review of drug transport mechanisms during lactation The literature review titled "A literature review of drug transport mechanisms during lactation," authored by…Certara2024 年 7 月 7 日