Central Nervous System (CNS) Archives | 第 2 页，共 6 页 | Certara

On-Demand Webinar

Using Virtual Twin Technology to Predict Drug Exposure in Individual Patients

In this webinar, Dr. Tom Polasek, a clinical pharmacologist at Certara Strategic Consulting, explained how…

webdev2018 年 3 月 8 日

Publication

Prediction of Olanzapine Exposure in Individual Patients Using Physiologically-based Pharmacokinetic Modeling and Simulation

webdev2017 年 11 月 30 日

Poster

Predicting Diclofenac Systemic and Synovial Fluid Concentrations After Dermal Application Using the Multi-phase Multi-layer MechDermA PBPK Model

webdev2017 年 6 月 6 日

Publication

Effect of Disease-related Changes in Plasma Albumin on the Pharmacokinetics of Naproxen in Male and Female Arthritic Rats

webdev2017 年 5 月 1 日

Publication

Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy

webdev2016 年 12 月 5 日

Publication

The Pharmacokinetics of Transdermal Flunixin Meglumine in Holstein Calves

This study describes the pharmacokinetics of topical and intravenous (IV) flunixin meglumine in Holstein calves.…

webdev2016 年 12 月 1 日

Publication

A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics

webdev2016 年 11 月 17 日

Blog

Modeling and Simulation Guides Dosing for a New Anti-psychotic Drug

Drug development is becoming more complex than ever. Regulatory agencies expect sponsors to consider a…

Karen Rowland Yeo2016 年 10 月 21 日

Publication

Pharmacokinetics and Tissue Elimination of Funixin in Veal Calves

OBJECTIVE To describe plasma pharmacokinetic parameters and tissue elimination of flunixin in veal calves. ANIMALS…

webdev2016 年 6 月 1 日

Publication

Development of a Permeability-limited Model of the Human Brain and Cerebrospinal Fluid (CSF) to Integrate Known Physiological and Biological Knowledge: Estimating Time Varying CSF Drug Concentrations and Their Variability Using In Vitro Data

A 4-compartment permeability-limited brain (4Brain) model consisting of brain blood, brain mass, cranial and spinal…

webdev2016 年 6 月 1 日

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