Historically, vaccine development and dose optimization have followed mostly empirical approaches without clinical pharmacology and model-informed approaches playing a major role, in contrast to conventional drug development. This is attributed to the complex cascade of immunobiological mechanisms associated with …
基于定量临床药理学的疫苗开发模型框架
2023 年 11 月 20 日
Author(s): Rajat Desikan,Massimiliano Germani, Piet H. van der Graaf, Mindy Magee
Year: 2023 年 11 月 2 日