Adding a Placebo Component to Your PK/PD Model in Phoenix
PK/PD modeling is an exciting are of research in clinical pharmacology. Most often we try…
Nathan Teuscher2014 年 8 月 20 日
FDA DataFit: an introduction
Explore FDA DataFit, a project ensuring high-quality, compliant data to streamline drug reviews, reduce delays,…
Certara2014 年 8 月 19 日
Lack of Angiopoietin-like-2 Expression Limits the Metabolic Stress Induced by a High-fat Diet and Maintains Endothelial Function in Mice
Angiopoietin-like-2 (angptl2) is produced by several cell types including endothelial cells, adipocytes and macrophages, and…
Danielle Pillsbury2014 年 8 月 15 日
Bioanalytical Calibration Curves
At the request of a reader, I have decided to extend my series on bioanalysis…
Nathan Teuscher2014 年 8 月 12 日
Assessment of Tumor Growth Inhibition Metrics to Predict Overall Survival
Modeling and simulation is proposed to support drug development phase transitions in oncology. Longitudinal tumor-size…
Danielle Pillsbury2014 年 8 月 1 日
Interaction Between Domperidone and Ketoconazole: Toward Prediction of Consequent QTc Prolongation Using Purely In Vitro Information
We aimed to investigate the application of combined mechanistic pharmacokinetic (PK) and pharmacodynamic (PD) modeling…
Danielle Pillsbury2014 年 8 月 1 日
