Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique Publication Quantification of drug metabolising enzymes and transporter proteins in the paediatric duodenum via LC-MS/MS proteomics using a QconCAT technique Characterising the small intestine absorptive membrane is essential to enable prediction of the systemic exposure…Certara2023 年 8 月 29 日
Certara Launches v11.0 of SEND Explorer Announcement Certara Launches v11.0 of SEND Explorer Delivers advanced data analysis and visualization capabilities to support nonclinical scientists PRINCETON, N.J.— August 28,…Certara2023 年 8 月 28 日
Payers’ reaction to the IRA’s Medicare Part D redesign Blog 付款人对IRA的医疗保险 Part D重新设计的反应 On 2022 年 8 月 16 日, President Biden signed the Inflation Reduction Act of 2022 (IRA) into…Certara2023 年 8 月 25 日
AMCP Poster – A survey-based analysis of the determinants of management in traditionally unmanaged categories of oncology and rare diseases Poster AMCP 海报 - 基于调查的肿瘤和罕见病传统管理类别决定因素分析 Certara2023 年 8 月 25 日
Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion Publication 开发并验证日本儿科生理药代动力学模型,重点关注通过细胞色素 P450 或肾脏排泄消除的药物 Physiologically based pharmacokinetic (PBPK) models are useful in bridging drug exposure in different ethnic groups,…Certara2023 年 8 月 21 日
Development and application of a PBPK modeling strategy to support antimalarial drug development Publication 开发和应用 PBPK 建模策略,支持抗疟疾药物开发 As part of a collaboration between Medicines for Malaria Venture (MMV), Certara UK and Monash…Certara2023 年 8 月 18 日
如果你的新分子实体没有明确的药物效应,请停止! 博客 如果你的新分子实体没有明确的药物效应,请停止! As a pharmacologist, I’ve always been curious about how drugs work. A favorite time-killer while…Certara2023 年 8 月 18 日
Computational neurosciences and quantitative systems pharmacology: a powerful combination for supporting drug development in neurodegenerative diseases Publication 计算神经科学和定量系统药理学:支持神经退行性疾病药物开发的强大组合 Successful clinical development of new therapeutic interventions is notoriously difficult, especially in neurodegenerative diseases, where…Certara2023 年 8 月 15 日
IRA impacts: First 10 drugs selected for the Drug Price Negotiation Program On-Demand Webinar IRA 影响:药品价格谈判计划选定的首批 10种药品 The Inflation Reduction Act (enacted in August 2022) contains profound changes for the healthcare and…Certara2023 年 8 月 15 日