Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus Poster 系统性红斑狼疮中联合靶向 BAFF 和 CD40 通路的定量系统药理学模型 Certara2024 年 11 月 22 日
Population pharmacokinetic modeling of niraparib to assess different absorption models Poster 尼拉帕利(Niraparib)群体药代动力学建模以评估不同吸收模型 Certara2024 年 11 月 22 日
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women Publication 定量药理学和系统药理学方法在改善和优化孕妇和哺乳期妇女药物治疗方面的最新应用 The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…Certara2024 年 11 月 18 日
Enhancing Pharmacokinetics Workflows at Charles River Case Study 优化 Charles River 实验室的药代动力学工作流程 PreclinicalPhoenix™ Integral Data Repository Charles River, a global leader in drug development, sought to improve…Certara2024 年 11 月 13 日
A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population Publication Zilovertamab Vedotin 在血液恶性肿瘤患者中的序贯群体药代动力学模型推断至儿童群体 Certara2024 年 11 月 7 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody Publication 通过对重组人单克隆抗体进行靶向药物处置建模和模拟,为妊娠剂量提供依据 The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…Certara2024 年 11 月 4 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Certara2024 年 10 月 30 日
On-ramps to popPK: Building Better Models with GUI, Code, or Both On-Demand Webinar popPK 建模入门指南:通过图形界面、代码或两者结合构建更优模型 A critical component of popPK studies is popPK modeling, where mathematical models are developed to…Certara2024 年 10 月 18 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Certara2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Certara2024 年 9 月 16 日