Modeling and Simulation Archives

Publication

通过对重组人单克隆抗体进行靶向药物处置建模和模拟，为妊娠剂量提供依据

The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…

Danielle Pillsbury2024 年 11 月 4 日

Publication

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

The article titled "Using PBPK modeling to supplement clinical data and support the safe and…

Danielle Pillsbury2024 年 10 月 30 日

On-Demand Webinar

popPK 建模入门指南：通过图形界面、代码或两者结合构建更优模型

A critical component of popPK studies is popPK modeling, where mathematical models are developed to…

Danielle Pillsbury2024 年 10 月 18 日

Publication

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…

Danielle Pillsbury2024 年 9 月 18 日

Publication

A tutorial on physiologically based pharmacokinetic approaches in lactation research

The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…

Danielle Pillsbury2024 年 9 月 16 日

Publication

美国 FDA 批准的新型药物应用基于生理的药代动力学模型应用

The article from the European Journal of Pharmaceutical Sciences reviews the role of Physiologically Based…

Danielle Pillsbury2024 年 9 月 1 日

Publication

预测涉及抑制作用的 CYP 介导的 DDIs：满足 Simcyp Simulator 系统鉴定要求的方法

The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…

Danielle Pillsbury2024 年 8 月 26 日

Publication

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…

Danielle Pillsbury2024 年 8 月 26 日

Podcast Video

Certara Talks: PAGE 2024

Learn more about our Modeling & Simulation Services Transcript: Hello, and welcome to Certara…

Certara2024 年 8 月 5 日

Publication

在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南

This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…

Danielle Pillsbury2024 年 7 月 24 日

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建模与模拟

通过对重组人单克隆抗体进行靶向药物处置建模和模拟，为妊娠剂量提供依据

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

popPK 建模入门指南：通过图形界面、代码或两者结合构建更优模型

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

A tutorial on physiologically based pharmacokinetic approaches in lactation research

美国 FDA 批准的新型药物应用基于生理的药代动力学模型应用

预测涉及抑制作用的 CYP 介导的 DDIs：满足 Simcyp Simulator 系统鉴定要求的方法

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

Certara Talks: PAGE 2024

在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南

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