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popPK 建模入门指南：通过图形界面、代码或两者结合构建更优模型

A critical component of popPK studies is popPK modeling, where mathematical models are developed to…

Certara2024 年 10 月 18 日

Conference

16th Annual World ADC London 2026

Certara2024 年 10 月 11 日

Publication

A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule‑1 Biomarker

Discover how PK‑TD modelling shows palonosetron reduces platinum exposure and KIM‑1 elevations versus other antiemetics…

Certara2024 年 9 月 20 日

Publication

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…

Certara2024 年 9 月 18 日

Publication

A tutorial on PBPK approaches in lactation research

Learn how physiologically based pharmacokinetic modeling can support drug transfer and infant exposure predictions during…

Certara2024 年 9 月 16 日

Publication

A tutorial on physiologically based pharmacokinetic approaches in lactation research

The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…

Certara2024 年 9 月 16 日

Publication

Intravenous Versus Intraosseous Use of Tranexamic Acid in Patients With Traumatic Brain Injury

See how IV and intraosseous TXA show similar total exposure in prehospital TBI care, analysed…

Certara2024 年 9 月 2 日

Publication

美国 FDA 批准的新型药物应用基于生理的药代动力学模型应用

The article from the European Journal of Pharmaceutical Sciences reviews the role of Physiologically Based…

Certara2024 年 9 月 1 日

Publication

Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome

Learn how triple‑drug combinations increase clobazam metabolite exposure and improve seizure control, modelled using Phoenix…

Certara2024 年 8 月 30 日

Publication

In Vivo Activity of Intestinal P-Glycoprotein and Hepatic Organic Anion Transporters Polypeptide in Pregnancy and Postpartum

Find out how rosuvastatin exposure increases during pregnancy due to reduced OATP activity, while P‑gp…

Certara2024 年 8 月 27 日

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建模与模拟

popPK 建模入门指南：通过图形界面、代码或两者结合构建更优模型

16th Annual World ADC London 2026

A Pharmacokinetic/Toxicodynamic Model of Cisplatin Nephrotoxicity Using the Kidney Injury Molecule‑1 Biomarker

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

A tutorial on PBPK approaches in lactation research

A tutorial on physiologically based pharmacokinetic approaches in lactation research

Intravenous Versus Intraosseous Use of Tranexamic Acid in Patients With Traumatic Brain Injury

美国 FDA 批准的新型药物应用基于生理的药代动力学模型应用

Utilizing an acute hyperthermia-induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome

In Vivo Activity of Intestinal P-Glycoprotein and Hepatic Organic Anion Transporters Polypeptide in Pregnancy and Postpartum

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