Model-Informed Drug Development in the Age of AI On-Demand Webinar 人工智能时代的模型引导的药物开发 Lorem ipsum dolor sit amet consectetur. Donec diam risus volutpat tempor. Massa accumsan aliquam nibh…Danielle Pillsbury2025 年 3 月 10 日
Postmarketing Assessment of Antibody–Drug Conjugates: Proof-of-Concept Using Model-Based Meta-Analysis and a Clinical Utility Index Approach Publication Postmarketing Assessment of Antibody–Drug Conjugates: Proof-of-Concept Using Model-Based Meta-Analysis and a Clinical Utility Index Approach This study explores a model-based meta-analysis (MBMA) and a clinical utility index (CUI) approach to…Danielle Pillsbury2025 年 3 月 4 日
Machine Learning for PK/PD Modeling in Drug Development Blog 药物开发中 PK/PD 建模的机器学习 Pharmacometricians can use machine learning for PK/PD modeling to help them characterize the safety and…Certara2025 年 3 月 4 日
Pharmacometrics Drug Development Decision Support: Model-Based Meta-Analysis (MBMA) Fact Sheet 定量药理学在药物开发中的决策支持:基于模型的荟萃分析(MBMA) Danielle Pillsbury2025 年 2 月 19 日
Certara’s Phoenix Platform – The world’s most trusted platform for PK/PD analysis and modeling Video Certara Phoenix 平台 — 全球最值得信赖的药代动力学/药效学(PK/PD)分析与建模平台 Today's drug candidates are more complex than ever. But with development decisions on the line,…Certara2025 年 2 月 12 日
Simulations to Inform Dose Selection for a Phase 2b Trial Investigating TOUR006, a Fully Human Anti-IL6 Antibody, for Treatment of Thyroid Eye Disease Poster 利用模拟结果为探索全人源抗 IL-6 抗体 TOUR006 治疗甲状腺眼病的 IIb 期试验确定剂量 Danielle Pillsbury2025 年 2 月 7 日
Machine Learning for Population PK Model Selection: Theory and Practice On-Demand Webinar 机器学习在群体药代动力学模型选择中的应用:理论与实践 Three of Certara's expert modelers provide a gentle introduction to machine learning in our field.…Danielle Pillsbury2025 年 2 月 7 日
Simcyp Version 24: Advancing PBPK capabilities and translating new science and technology into regulatory-accepted predictive modeling On-Demand Webinar Simcyp Version 24: Advancing PBPK capabilities and translating new science and technology into regulatory-accepted predictive modeling With the release of Version 24, the Simcyp Simulator introduces cutting-edge enhancements that further elevate…Danielle Pillsbury2025 年 2 月 7 日
Population Pharmacokinetic and Pharmacodynamic Analysis of Navtemadlin in Patients with Relapsed and Refractory (R/R) Myelofibrosis (MF) and Other Myeloid or Solid Tumor Malignancies Publication 针对复发难治性(R/R)骨髓纤维化(MF)及其他髓系或实体瘤恶性肿瘤患者的 Navtemadlin 群体药代动力学与药效学分析 This study conducted a population pharmacokinetic (PK) and pharmacodynamic (PD) analysis of navtemadlin, an MDM2…Danielle Pillsbury2025 年 2 月 6 日
Understanding Variability in CAR-T Cell Therapy Kinetics Publication 了解 CAR-T 细胞疗法动力学的变异性 Axicabtagene ciloleucel (axi-cel), a CAR-T cell therapy for relapsed and refractory non-Hodgkin’s lymphoma (NHL), demonstrates…Danielle Pillsbury2025 年 1 月 23 日