Population-based Mechanistic Prediction of Oral Drug Absorption Publication Population-based Mechanistic Prediction of Oral Drug Absorption The bioavailability of drugs from oral formulations is influenced by many physiological factors including gastrointestinal…Certara2009 年 6 月 1 日
Accurate and Interpretable Computational Modeling of Chemical Mutagenicity Publication Accurate and Interpretable Computational Modeling of Chemical Mutagenicity We describe a method for modeling chemical mutagenicity in terms of simple rules based on…Certara2008 年 9 月 5 日
A Novel Druglike Spleen Tyrosine Kinase Binder Prevents Anaphylactic Shock when Administered Orally Publication A Novel Druglike Spleen Tyrosine Kinase Binder Prevents Anaphylactic Shock when Administered Orally BACKGROUND: The spleen tyrosine kinase (Syk) is recognized as a potential pharmaceutical target for the…Certara2008 年 7 月 1 日
A Phospho-sugar Binding Domain Homologous to NagB Enzymes Regulates the Activity of the Central Glycolytic Genes Repressor Publication A Phospho-sugar Binding Domain Homologous to NagB Enzymes Regulates the Activity of the Central Glycolytic Genes Repressor CggR belongs to the SorC family of bacterial transcriptional regulators which control the expression of…Certara2008 年 6 月 1 日
In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators Publication In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators Early identification of adverse effect of preclinical and commercial drugs is crucial in developing highly…Certara2007 年 11 月 1 日