Indirect Exposure-Response Modeling for Transthyretin Amyloid Cardiomyopathy Treated with Acoramidis (AG10) Poster 转甲状腺素蛋白淀粉样变性心肌病经 Acoramidis(AG10)治疗的间接暴露-反应建模 Danielle Pillsbury2024 年 11 月 22 日
Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen Poster 增强型确定性筛选设计为 CAR-T 细胞和淋巴清除疗法的 1 期筛选提供了高效率 Danielle Pillsbury2024 年 11 月 22 日
Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials Poster 肿瘤学 MIDD 模拟器 — 用于早期肿瘤学试验总生存期预测的用户友好型应用程序 Danielle Pillsbury2024 年 11 月 22 日
Population pharmacokinetic modeling of niraparib to assess different absorption models Poster 尼拉帕利(Niraparib)群体药代动力学建模以评估不同吸收模型 Danielle Pillsbury2024 年 11 月 22 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody Publication 通过对重组人单克隆抗体进行靶向药物处置建模和模拟,为妊娠剂量提供依据 The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…Danielle Pillsbury2024 年 11 月 4 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Danielle Pillsbury2024 年 10 月 30 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Danielle Pillsbury2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Danielle Pillsbury2024 年 9 月 16 日
A literature review of drug transport mechanisms during lactation Publication A literature review of drug transport mechanisms during lactation The literature review titled "A literature review of drug transport mechanisms during lactation," authored by…Danielle Pillsbury2024 年 7 月 7 日
Simcyp Simulator Helps Optimize Drug Dosing in Adults & Adolescents with Orphan Disease Case Study Simcyp Simulator 有助于优化成人和青少年孤儿病患者的用药剂量 全世界约有 400,000 名先天性肾上腺增生症(CAH)患者。Current therapy for CAH uses a…Becca Bucci2022 年 6 月 6 日