Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women Publication 定量药理学和系统药理学方法在改善和优化孕妇和哺乳期妇女药物治疗方面的最新应用 The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…Certara2024 年 11 月 18 日
Why clinical pharmacology & pharmacometrics should collaborate Blog 临床药理学与定量药理学为何要合作 A symbiosis between a modeler and a trialist is often required to develop a model-informed…Certara2024 年 11 月 8 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody Publication 通过对重组人单克隆抗体进行靶向药物处置建模和模拟,为妊娠剂量提供依据 The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…Certara2024 年 11 月 4 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Certara2024 年 10 月 30 日
Curing Data Collection Woes Could Take a Village Press Coverage Curing Data Collection Woes Could Take a Village The article "Curing Data Collection Woes Could Take a Village" explores the challenges of clinical…Certara2024 年 10 月 8 日
How clinical trial technology streamlines the research process Blog 临床试验技术如何简化研究过程 Learn how innovative clinical trial technology helps to revolutionize research & ensure the swift rollout…Gilbert Hunter2024 年 9 月 25 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Certara2024 年 9 月 18 日
A tutorial on physiologically based pharmacokinetic approaches in lactation research Publication A tutorial on physiologically based pharmacokinetic approaches in lactation research The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…Certara2024 年 9 月 16 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator Publication 预测涉及抑制作用的 CYP 介导的 DDIs:满足 Simcyp Simulator 系统鉴定要求的方法 The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…Certara2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) Publication Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH) The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…Certara2024 年 8 月 26 日