Clinical Trials Software Archives

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Piet van der Graaf 谈人工智能和人工智能辅助药物研发方法

At the 2024 AAPS PharmSci 360 conference, Bioanalysis Zone interviewed Piet van der Graaf, Senior…

Certara2024 年 12 月 10 日

Publication

通过对重组人单克隆抗体进行靶向药物处置建模和模拟，为妊娠剂量提供依据

The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…

Danielle Pillsbury2024 年 11 月 4 日

Publication

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

The article titled "Using PBPK modeling to supplement clinical data and support the safe and…

Danielle Pillsbury2024 年 10 月 30 日

Publication

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…

Danielle Pillsbury2024 年 9 月 18 日

Publication

A tutorial on physiologically based pharmacokinetic approaches in lactation research

The tutorial by Amita Pansari, Xian Pan, Lisa M. Almond, and Karen Rowland-Yeo examines the…

Danielle Pillsbury2024 年 9 月 16 日

Publication

预测涉及抑制作用的 CYP 介导的 DDIs：满足 Simcyp Simulator 系统鉴定要求的方法

The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…

Danielle Pillsbury2024 年 8 月 26 日

Publication

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…

Danielle Pillsbury2024 年 8 月 26 日

Publication

在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南

This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…

Danielle Pillsbury2024 年 7 月 24 日

Publication

A literature review of drug transport mechanisms during lactation

The literature review titled "A literature review of drug transport mechanisms during lactation," authored by…

Danielle Pillsbury2024 年 7 月 7 日

Publication

Simcyp 群体模拟器中 PBPK 建模复合文件开发指南

The Simcyp Simulator is a software platform for population physiologically-based pharmacokinetic (PBPK) modeling and simulation.…

Jim Gallagher2024 年 2 月 23 日

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Clinical Trials Software

Piet van der Graaf 谈人工智能和人工智能辅助药物研发方法

通过对重组人单克隆抗体进行靶向药物处置建模和模拟，为妊娠剂量提供依据

Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women

A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk

A tutorial on physiologically based pharmacokinetic approaches in lactation research

预测涉及抑制作用的 CYP 介导的 DDIs：满足 Simcyp Simulator 系统鉴定要求的方法

Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)

在 Simcyp Simulator 中开发基于生理的药代动力学模型人群文件指南

A literature review of drug transport mechanisms during lactation

Simcyp 群体模拟器中 PBPK 建模复合文件开发指南

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