Predicting and Taming Immunogenicity: Strategies for your Biologic Drug
Immunogenicity is the ability of a foreign substance, such as a drug or vaccine, to…
Certara2021 年 11 月 19 日
Dose Optimization Using Population PK for an Orphan Drug
RAPALIMUS® Tablets (sirolimus) is Nobelpharma’s orphan drug developed from an oral medication that is sold…
Certara2021 年 11 月 17 日
A Day in the Life of a Clinical Pharmacology Consultant
Strategic consulting within drug discovery and development is an exciting career choice for many. Unlike…
Certara2021 年 10 月 8 日
Building a Robust Clinical Pharmacology & Model-Informed Drug Development Strategy for New Alzheimer’s Disease Drugs
Alzheimer's disease (AD) is one of the most common forms of neurodegenerative dementia in the…
Certara2021 年 9 月 20 日
生物制剂的临床药理计划是怎样的？
Monoclonal antibodies are now widely used in the treatment of several diseases, providing effective and…
Certara2021 年 8 月 6 日
Key Considerations to Ensure Maximal Probability of Antibody Drug Conjugate Development Success
Antibody drug conjugates (ADC) are a unique way to obliterate tumor cells and represent an…
Certara2021 年 7 月 8 日
8 Tips for Successfully Developing Oligonucleotide Therapies
By Eva Gil Berglund and Nathalie H Gosselin Oligonucleotide therapeutics are a validated class of…
Certara2021 年 2 月 1 日
“Where do I start?”: Strategies for selecting the first dose for human clinical trials
This guide to dose selection for first-in-human studies explains the conceptual framework, methods, and tools…
Certara2020 年 12 月 22 日
Clinical Pharmacology Gap Analysis: Lessons Learned
Clinical pharmacology gap analysis is a tool for outlining your drug program’s needs, prioritizing these…
Certara2018 年 8 月 10 日
