Improved Translation of Clinical TCE Dosing with Mechanistic Modeling Blog Post
摘要：主讲人：Marc Presler, PhD, Associate Director, QSP 录制于 2023 年 7 月 20 日, 星期四；这项工作最初由 Applied BioMath 提出。Applied BioMath was acquired by Certara in December…
Applications of a QSP Model of LNP mRNA Delivery for the Treatment of Crigler-Najjar Syndrome Type 1 Blog Post
摘要：主讲人：Diana Marcantonio, PhD, Senior Director, QSP Recorded on 2023 年 9 月 21 日. This work was initially presented by Applied BioMath. Applied BioMath was acquired by Certara in December 2023.
Guiding Target and Lead Optimization for a Molecular Glue Degrader Blog Post
Learn how to optimize drug properties for protein degrader therapeutics by exploring system characteristics.
Capturing CAR T-cell Therapy Dynamics Through Mechanistic Modeling Blog Post
摘要：Chimeric antigen receptor T (CAR T)-cell therapy has shown remarkable success in treating various leukemias and lymphomas. CARs are engineered to redirect T cells to specific antigens. Much is still…
Physiologically Based Pharmacokinetic Modelling, an Integrative Approach to First in Human (FIH) Studies [APAC Webinar] Blog Post
Summary Physiologically Based Pharmacokinetic (PBPK) modelling is an integrative approach facilitating the optimal use of various in vitro and preclinical data to determine the first in human dose. Simcyp Discovery&...
Part 5: Regulatory Outlook on Data Management Blog Post
In this video interview with ACT editor Andy Studna, Erin Erginer, director of product, Certara looks forward and shares her insights on the future of data management.
Part 4: Consequences of Improper Data Collection Blog Post
In this video interview with ACT editor Andy Studna, Erin Erginer, director of product, Certara discusses how improper data collection can extend timelines and incur additional cost.
Part 3: Ensuring Proper Data Collection Blog Post
In this video interview with ACT editor Andy Studna, Erin Erginer, director of product, Certara touches on the burden associated with data collection.
Part 2: Regulatory Challenges With Data Collection Blog Post
In this video interview with ACT editor Andy Studna, Erin Erginer, director of product, Certara discusses the lack of submission standards for clinical data.
