Publication Archives

Publication

Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

Madin–Darby canine kidney (MDCK) cells are widely used to study epithelial cell functionality. Their low…

Certara2023 年 6 月 28 日

Publication

Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper

The promise of viral vector-based gene therapy (GT) as a transformative paradigm for treating severely…

Certara2023 年 6 月 14 日

Publication

QSP Designer: Quantitative systems pharmacology modeling with modular biological process map notation and multiple language code generation

Typical Quantitative Systems Pharmacology (QSP) workflows involve discussion of biology, supported by graphical diagrams, followed…

Certara2023 年 5 月 25 日

Publication

Exposure-Response Analyses of Tremelimumab Monotherapy or in Combination with Durvalumab in Patients with Unresectable Hepatocellular Carcinoma

An novel single dose regimen of tremelimumab combined with durvalumab could be a way to…

Certara2023 年 1 月 26 日

Publication

ScienceDirect: Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trial

Observational studies have postulated a therapeutic role of metformin in treating COVID-19. We conducted ...(cont.)

Certara2021 年 12 月 22 日

Publication

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

Drug repurposing is promoted as a cost- and time-effective mechanism for providing new medicines. Often,…

Certara2021 年 9 月 23 日

Publication

应用定量系统药理学（QSP）指导 COVID-19 疫苗最佳剂量方案

Optimal use and distribution of coronavirus disease 2019 (COVID-19) vaccines involves adjustments of dosing. Due…

Certara2021 年 7 月 31 日

Publication

Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate

As model‐informed drug development becomes an integral part of modern approaches to the discovery of…

Certara2021 年 5 月 13 日

Publication

Blueprint for pandemic response: Focus on translational medicine, clinical pharmacology and pharmacometrics

Perhaps the most important lesson learned from the COVID‐19 pandemic is that of preparedness. Enhanced…

Certara2021 年 5 月 11 日

Publication

Economic and Clinical Burden of Virus-Associated Hemorrhagic Cystitis in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation in the United States

Authors: Joseph McGuirk, Clint Divine, Seung Hyun Moon, Aastha Chandak, Zhiji Zhang, Genovefa A. Papanicolaou…

Certara2021 年 4 月 8 日

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Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

Model-Informed Approaches and Innovative Clinical Trial Design for Adeno-Associated Viral Vector-Based Gene Therapy Product Development: A White Paper

QSP Designer: Quantitative systems pharmacology modeling with modular biological process map notation and multiple language code generation

Exposure-Response Analyses of Tremelimumab Monotherapy or in Combination with Durvalumab in Patients with Unresectable Hepatocellular Carcinoma

ScienceDirect: Effect of early treatment with metformin on risk of emergency care and hospitalization among patients with COVID-19: The TOGETHER randomized platform clinical trial

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

应用定量系统药理学（QSP）指导 COVID-19 疫苗最佳剂量方案

Opening a debate on open‐source modeling tools: Pouring fuel on fire versus extinguishing the flare of a healthy debate

Blueprint for pandemic response: Focus on translational medicine, clinical pharmacology and pharmacometrics

Economic and Clinical Burden of Virus-Associated Hemorrhagic Cystitis in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation in the United States

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