Understanding LC/MS/MS
The most common bioanalytical method in use today is LC/MS/MS, or liquid chromatography (LC) tandem…
Certara2014 年 7 月 15 日
What Can We Learn from Dose Normalization?
Dose normalization is a common calculation performed with pharmacokinetic parameters. The general process is to…
Certara2014 年 5 月 19 日
Hyperlinking: Making the Most of Navigation in eCTD Submissions
When authors generate documents intended for electronic submission they use blue-colored font to indicate where…
Certara2014 年 2 月 5 日
What is GLP (Good Laboratory Practice)?
Good laboratory practice or GLP is a set of principles intended to assure the quality…
Certara2013 年 12 月 9 日
Understanding Steady State Pharmacokinetics
Register for our July 10 webinar and discover fast, flexible, frictionless PK/PD workflows with Phoenix…
Certara2013 年 11 月 25 日
Mean Residence Time (MRT): Understanding How Long Drug Molecules Stay in the Body
When I first began learning about pharmacokinetics, I was often confused by the mean residence…
Certara2013 年 3 月 28 日
What is a Loading Dose?
Drug therapy in chronic disease situations requires systemic drug levels to reach target steady-state levels…
Certara2013 年 3 月 22 日
Nonlinear PK: What Does That Mean?
You may come across a phrase like the following and wonder what it means: “……
Certara2013 年 2 月 17 日
Calculating Urine PK Parameters
Pharmacokinetic analysis normally focuses on systemic exposure to a drug; however, much can be learned…
Certara2012 年 12 月 6 日
Bioavailability
Discover bioavailability in pharmacokinetics, its types, the first-pass effect, and calculations. Explore tools for accurate…
Certara2012 年 11 月 4 日
